D2H2 Bioassay

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Central to the realization of Distributed Diagnosis and Home Healthcare and distributed medical diagnosis is the availability of portable, robust and low-cost diagnostic instruments. Commercially available instruments are generally bulky, complex and expensive. A portable instrument capable of carrying out real-time medical diagnosis using only a minute amount of biological fluid from the patient needs to be developed. Under D2H2, the Bioassay group is dedicated in the development of techniques and equipment for the quantitative and qualitative analysis of biological markers. There are three different initiatives that is the core of the group’s research, namely, biosensing, microfluidics and biochemistry.  

In biosensing, both optical and electronic techniques are explored. For optical techniques, detection of analytes using fluorescence and surface plasmon resonance forms our main research direction. Using high dielectric materials to develop electronic biosensors are also being explored. In microfluidics, our main focus lie in microfluidic channel design and fabrication, as well as development of microfluidic channel pumps. Our focus in biochemistry is on surface modification of certain materials such that bioreceptors can be attached easily to these surfaces. Fluorescence tagging of certain analytes are important, so that these analytes can be detected using our fluorescence sensors.

                              Overview of the Bioassay group’s research initiatives

 Bioassay Teamsite Link

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Copyright © 2005 Singapore-University of Washington Alliance in Bioengineering
Last modified: 28 April 2006