1. G.E. Davey*, Z. Adhireksan*, Z. Ma*, T. Riedel*, D. Sharma, S. Padavattan, D. Rhodes, A. Ludwig, S. Sandin, B.S. Murray, P.J. Dyson & C.A. Davey. 2017. Nucleosome Acidic Patch-Targeting Binuclear Ruthenium Compounds Induce Aberrant Chromatin Condensation. Nature Commun. 8(1): #1575.
  2. R.F.S Lee, T. Riedel, S. Escrig, C. Maclachlan, G.W. Knott, C.A. Davey, K. Johnsson, A. Meibom & P.J. Dyson. 2017. Differences in cisplatin distribution in sensitive and resistant ovarian cancer cells: a TEM/NanoSIMS study. Metallomics. 9(10): 1413-1420.
  3. Z. Adhireksan*, G. Palermo*, T. Riedel*, Z. Ma*, R. Muhammad, U. Rothlisberger, P.J. Dyson & C.A. Davey. 2017. Allosteric cross-talk in chromatin can mediate drug-drug synergy. Nature Commun. 8: #14,860.
  4. M. Hanif, S.M. Meier, Z. Adhireksan, H. Henke, S. Martic, S. Movassaghi, M. Labib, W. Kandioller, S.M.F. Jamieson, M. Hejl, M.A. Jakupec, H.B. Kraatz, C.A. Davey, B.K. Keppler & C.G. Hartinger. 2017. The Functionalization of RuII(n^6-p-cymene)(3-hydroxy-2-pyridone) Complexes with (Thio)Morpholine: Synthesis and Bioanalytical Studies. ChemPlusChem. 82(6): 841-847.
  5. Z. Ma*, G. Palermo*, Z. Adhireksan*, B.S. Murray, T. von Erlach, P.J. Dyson, U. Rothlisberger & C.A. Davey. 2016. An Organometallic Compound which Exhibits a DNA Topology-Dependent One-Stranded Intercalation Mode. Angew. Chem. Int. Ed. 55(26): 7441-7444.
  6. G. Palermo, A. Magistrato, T. Riedel, T. von Erlach, C.A. Davey, P.J. Dyson & U. Rothlisberger. 2016. Fighting Cancer with Transition Metal Complexes: From Naked DNA to Protein and Chromatin Targeting Strategies. ChemMedChem. 11(12): 1199-1210.
  7. R.F.S. Lee, S. Escrig, M. Croisier, S. Clerc-Rosset, G.W. Knott, A. Meibom, C.A. Davey, K. Johnsson & P.J. Dyson. 2015. NanoSIMS Analysis of an Isotopically Labelled Organometallic Ruthenium(II) Drug to Probe Its Distribution and State In Vitro. Chem. Commun. 51(92): 16,486-16,489.
  8. E.Y.D. Chua*, G.E. Davey*, C.F. Chin*, P. Dröge, W.H. Ang & C.A. Davey. 2015. Stereochemical Control of Nucleosome Targeting by Platinum-Intercalator Antitumour Agents. Nucleic Acids Res. 43(11): 5284-5296.
  9. C.A. Davey. 2015. Exposure to Metals Can Be Therapeutic. Chimia. 69(3): 125-130.
  10. Z. Adhireksan*, G.E. Davey*, P. Campomanes*, M. Groessl, C.M. Clavel, H. Yu, A.A. Nazarov, H.F. Yeo, W.H. Ang, P. Dröge, U. Rothlisberger, P.J. Dyson & C.A. Davey. 2014. Ligand Substitutions between Ruthenium-Cymene Compounds Can Control Protein versus DNA Targeting and Anticancer Activity. Nature Commun. 5: #3462.
  11. C.A. Davey. 2013. Does the Nucleosome Break Its Own Rules? Curr. Opin. Struct. Biol. 23(2): 311-313.
  12. S.M. Meier, M. Hanif, Z. Adhireksan, V. Pichler, M. Novak, E. Jirkovsky, M.A. Jakupec, V.B. Arion, C.A. Davey, B.K. Keppler & C.G. Hartinger. 2013. Novel Metal(II) Arene 2-Pyridinecarbothioamides: A Rational to Orally Active Organometallic Anticancer Agents. Chem. Sci. 4(4): 1837-1846.
  13. E.Y.D. Chua*, D. Vasudevan*, G.E. Davey, B. Wu & C.A. Davey. 2012. The Mechanics Behind DNA Sequence-Dependent Properties of the Nucleosome. Nucleic Acids Res. 40(13): 6338-6352.
  14. B. Wu, G.E. Davey, A. Nazarov, P.J. Dyson & C.A. Davey. 2011. Specific DNA Structural Attributes Modulate Platinum Anticancer Drug Site Selection and Cross-Link Generation. Nucleic Acids Res. 39(18): 8200-8212.
  15. B. Wu*, M.S. Ong*, M. Groessl, Z. Adhireksan, C.G. Hartinger, P.J. Dyson & C.A. Davey. 2011. A Ruthenium Antimetastasis Agent Forms Specific Histone Protein Adducts in the Nucleosome Core. Chemistry. 17(13): 3562-3566.
  16. S. Tan & C.A. Davey. 2011. Nucleosome Structural Studies. Curr. Opin. Struct. Biol. 21(1): 128-136.
  17. A. Allahverdi, R. Yang, N. Korolev, Y. Fan, C.A. Davey, C.F. Liu & L. Nordenskiöld. 2010. The Effects of Histone H4 Tail Acetylations on Cation-Induced Chromatin Folding and Oligomerization. Nucleic Acids Res. 39(5): 1680-1691.
  18. M.S. Ong*, D. Vasudevan* & C.A. Davey. 2010. Divalent Metal- and High Mobility Group N Protein-Dependent Nucleosome Stability and Conformation. J. Nucleic Acids. 2010: 143890.
  19. D. Vasudevan, E.Y.D. Chua & C.A. Davey. 2010. Crystal Structures of Nucleosome Core Particles Containing the ‘601’ Strong Positioning Sequence. J. Mol. Biol. 403(1): 1-10.
  20. K. Mohideen, R. Muhammad & C.A. Davey. 2010. Perturbations in Nucleosome Structure from Heavy Metal Association. Nucleic Acids Res. 38(18): 6301-6311.
  21. B. Wu & C.A. Davey. 2010. Using Soft X-Rays for a Detailed Picture of Divalent Metal Binding in the Nucleosome. J. Mol. Biol. 398(5): 633-640.
  22. B. Wu*, K. Mohideen*, D. Vasudevan & C.A. Davey. 2010. Structural Insight into the Sequence Dependence of Nucleosome Positioning. Structure. 18(4): 528-536.
  23. G.E. Davey*, B. Wu*, Y. Dong, U. Surana & C.A. Davey. 2010. DNA Stretching in the Nucleosome Facilitates Alkylation by an Intercalating Antitumour Agent. Nucleic Acids Res. 38(6): 2081-2088.
  24. B. Wu & C.A. Davey. 2008. Platinum Drug Adduct Formation in the Nucleosome Core Alters Nucleosome Mobility but not Positioning. Chem. Biol. 15(10): 1023-1028.
  25. G.E. Davey & C.A. Davey. 2008. Chromatin- a New, Old Drug Target? Chem. Biol. Drug Des. 72(3): 165-170.
  26. B. Wu, P. Dröge & C.A. Davey. 2008. Site Selectivity of Platinum Anticancer Therapeutics. Nature Chem. Biol. 4(2): 110-112. “Platinum Result” in Research Highlights. 2008. Nature. 451(7175): 111.
  27. P. Dröge & C.A. Davey. 2008. Do Cells let-7 Determine Stemness? Cell Stem Cell. 2(1): 8-9.
  28. M.S. Ong, T.J. Richmond & C.A. Davey. 2007. DNA Stretching and Extreme Kinking in the Nucleosome Core. J. Mol. Biol. 368(4): 1067-1074.
  29. Q. Bao, H. Chen, Y. Liu, J. Yan, P. Dröge & C.A. Davey. 2007. A Divalent Metal-mediated Switch Controlling Protein-induced DNA Bending. J. Mol. Biol. 367(3): 731-740.
  30. O. Li, D. Vasudevan, C.A. Davey & P. Dröge. 2006. High-Level Expression of DNA Architectural Factor HMGA2 and Its Association with Nucleosomes in Human Embryonic Stem Cells. Genesis. 44(11): 523-529.

ETH-Zurich, Switzerland

  1. T.J. Richmond & C.A. Davey. 2003. The Structure of DNA in the Nucleosome Core. Nature. 423(6936): 145-150.
  2. E. Eichhorn, C.A. Davey, D.F. Sargent, T. Leisinger & T.J. Richmond. 2002. Crystal Structure of Escherichia coli Alkanesulfonate Monooxygenase SsuD. J. Mol. Biol. 324(3): 457-468.
  3. C.A. Davey & T.J. Richmond. 2002. DNA-Dependent Divalent Cation Binding in the Nucleosome Core Particle. Proc. Natl. Acad. Sci. USA 99(17): 11169-11174.
  4. C.A. Davey, D.F. Sargent, K. Luger, A.W. Mäder & T.J. Richmond. 2002. Solvent Mediated Interactions in the Structure of the Nucleosome Core Particle at 1.9 Å Resolution. J. Mol. Biol. 319(5): 1097-1113.

University of Miami, USA

  1. C.A. Davey, T. Fiedler & R.E. Fenna. 2000. Chap. 4: "X-Ray Crystallographic Studies of Human Myeloperoxidase." in "The Peroxidase Multigene Family of Enzymes: Biochemical Basis and Clinical Applications." P.E. Petrides & W.M. Nauseef, Eds. Springer-Verlag: Berlin, New York.
  2. T.J. Fiedler, C.A. Davey & R.E. Fenna. 2000. X-Ray Crystal Structure and Characterization of Halide-binding Sites of Human Myeloperoxidase at 1.8 Å Resolution. J. Biol. Chem. 275(16): 11964-11971.
  3. C.A. Davey & R.E. Fenna. 1996. 2.3 Å Resolution X-Ray Crystal Structure of the Bi-Substrate Analogue Inhibitor Salicylhydroxamic Acid Bound to Human Myeloperoxidase: A Model for a Pre-Reaction Complex with Hydrogen Peroxide. Biochemistry. 35(33): 10967-10973.
  4. C. Davey, A. Jacquet, N. Moguilevsky & R.E. Fenna. 1995. Characterization of the Heme-Protein Covalent Bonds in Human Myeloperoxidase by X-Ray Crystallography and Site Directed Mutagenesis. Protein Engineering. 8(suppl.): 112.
  5. R. Fenna, J. Zeng & C. Davey. 1995. Structure of the Green Heme in Myeloperoxidase. Arch. Biochem. Biophys. 316: 653-656.

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