PUBLICATIONS, PATENTS AND BOOK CHAPTERS

Journal Papers  

1. Xiong Xiao, Han Ding, Xinyu Fang and Xue-Wei Liu*, A Proton-Free Strain-Release Glycosylation via Ring-Opening of Cyclopropane, Angew. Chem. Int. Ed. 2022, submitted.

2. Qiu-Qi Mu†*, Ao-Xin Guo†, Yang-Yang Qin, Xin-Yu Fang, Li-Cong Peng, Xin Cai, Chao Feng, Xiong Xiao, Xue-Wei Liu*. A Combined Experimental and Computational Mechanistic Investigation of Iridium-Catalyzed Unusual Anomerization of C-Glycosides, Nature Catalysis, 2022, submitted.

3. Xu, Y.; Song, S.; He, J.; Chan-Park, M. B.; Cao, H.; Deng, Y. Liu, X.-W.* Peptidoglycan Oligomer-based Broad-spectrum Immunotherapeutics against Microbial Infection by Recruiting Endogenous Antibodies, Nat. Microbiol. 2022, submitted.

4. Báti Gábor+, Xiao-Lin Zhang+, Chenyu Li, Claresta Yeo, Kumar Bhaskar Pal, Yuan Xu, Yuan Qiao*, and Xue-Wei Liu*. Rapid Access to Bacterial Cell Wall Feedstock: GluNAc-1,6 anhydro-MurNAc as the Glycosyl Acceptor of Transglycosylase, Angew. Chem. Int. Ed. 2022, submitted.

5. Siai Zhou, Xuemei Zhong, Aoxin Guo, Qian Xiao, Jiaming Ao, Wanmeng Zhu, Hui Cai, Akihiro Ishiwata*, Yukishige Ito,* Xue-Wei Liu,* Feiqing Ding.* ZnI2-Directed Stereocontrolled α-Glucosylation, Org. Lett. 2021, 23, 6841-6845.

6. Xuemei Zhong, Siai Zhou, Jiaming Ao, Aoxin Guo, Qian Xiao, Yan Huang, Wanmeng Zhu, Hui Cai, Akihiro Ishiwata*, Yukishige Ito, Xue-Wei Liu*, and Feiqing Ding.* Zinc(II) Iodide-Directed β-Mannosylation: Reaction Selectivity, Mode, and Application, J. Org. Chem. 2021, 86, 16901-16915.

7. Yang, Y. M.; Zhang, Y. J. Qu, Y. Y.; Zhang, C.; Liu, X.-W.; Zhao, M. W.; Mu, Y. G.*; Li, W.-F.* Key residues of the receptor binding domain in the spike protein of SARS-CoV-2 mediating the interactions with ACE2: a molecular dynamics study, Nanoscale, 2021, 13, 9364-9370.

8. Yip, B. R. P.; Pal, K. B.; Lin, J. D.; Xu, Y.; Das, M.; Lee, J. D.; Liu, X.-W.* Easy access to secondary and tertiary alcohols via metal-free and light mediated radical carbonyl allylation, Chem. Comm. 2021, 57, 10783-10786.

9. Weiwei Fang, Yinghua Lv, Zelong Chen, Feng Wang, Yi Wang, Yuxin Pei*, Wenjuan Jin, Chaojie Shi, Yang Wang, Yun Qu, Wei Ji, Liang Pu, Xue-Wei Liu*, Zhichao Pei*. A carrier-free multifunctional nano photosensitizer based on self-assembly of lactose-conjugated BODIPY for enhanced anti-tumor efficacy of dual phototherapy, Chem. Eng. J. 2021, 417, 129178.

10. Kumar Bhaskar Pal, Aoxin Guo, Mrinmoy Das, Jiande Lee, Gábor Báti, Benjamin Rui Peng Yip, Teck-Peng Loh and Xue-Wei Liu*. Iridium-promoted Deoxyglycoside Synthesis: Stereoselectivity and Mechanistic Insight. Chem.Sci. 2021, 12, 2209-2216.

11. Qiu-Chao Mu*, Yi-Xue Nie, Hang Li, Xing-Feng Bai, Xue-Wei Liu, Zheng Xu, Li-Wen Xu*. Catalytic asymmetric oxidative carbonylation –induced kinetic resolution of sterically hindered benzylamines to chiral isoindolinones. Chem. Comm. 2021, 57, 1778-1781.

12. Yuan Xu, Hongbin Zhang, Xue–Wei Liu,* Carbohydrate-Containing Macromolecules for Antimicrobial Applications: With an Emphasis on Synthetic Glycopolymers, J. Org. Chem. 2021, doi.org/10.1021/acs.joc.0c01597.

13. Yuan Xu, Xin Ge, Yuhan Zhang, Hongbin Zhang, and Xue-Wei Liu*. A Mild One-pot Synthesis to 2-Iminothiazolines from Thioureas and 1-Bromo-1-nitroalkenes. RSC Adv. 2021, 11, 2221-2225.

14. Yuan Xu and Xue-Wei Liu,* The Versatility of Carbohydrates in Antimicrobial Applications, J. Chin. Chem. Soc. 2020, 67, 2204-2207. Invited for Special Issue Paper-18th Asian Chemical Congress.

15. Kumar Bhaskar Pal, Aoxin Guo, Mrinmoy Das, Gabor Bati, Xue-Wei Liu,* Superbase-catalyzed Stereo- and Regioselective Glycosylation with 2-Nitroglycals: Facile Access to 2-Amino-2-deoxy-O-glycosides, ACS Catal. 2020, 10, 6707-6715.

16. Junjie Desmond Lin, Xue-Wei Liu,* Recent Development in Ligation Methods for Glycopeptide and Glycoprotein Synthesis. Chem. Asian J. 2020, 15, 2548-2557.

17. Jingxi He, Kim Le Mai Hoang, Shu Hui Kho, Zhong Guo, Kishore R. Venkata, Rubi Z. Vazquez, Sin Ni Hoo, Hongwei Duan, Mary B. Chan-Park and Xue-Wei Liu, Synthesis of biohybrid peptidoglycan oligomers that incorporate into bacterial cell walls, Chem. Sci., 2020, 11, 3171-3179.

18. Rajan, S.; Jang, Y.; Kim, C.-H.; Toh, H. T.; Jeon, J.; Song, B.; Maqueda, A. S.; Lescar, J.; Shin, J.; Liu, X.-W.; Feitosa, M.; Hwang, D.; Lim, K.-L.; Park, H. M.; Lee, C. H.; Petsko, G.; Yoon, H. S. Co-crystal structure and function of Nurr1 bound to the cyclopentenone prostaglandin A1. Nat. Chem. Biol. 2020, 16, 876-886.

19. Pal, K. B.; Lee, J.; Das, M.; Liu, X.-W. Palladium(II)-catalyzed stereoselective synthesis of C-glycosides from glycals with diaryliodonium salts. Org. Biomol. Chem. 2020, 18, 2242-2251.

20. **Guo, Z.; *He, J.-X.; Mahadevegowda, S. H.; *Kho, S. H.; Chan-Park, M. B.; Liu, X.-W. Multifunctional Glyco-Nanosheets to Eradicate Drug-Resistant Bacteria on Wounds. Adv. Health Mat. 2020, 9, 2000265. Highlighted by X-MOL.

21. **Pal, K. B.; *Guo, A.; *Das, M.; *Báti, G.; Chan-Park, M. B.; Liu, X.-W. Phosphazene base-catalysed stereo and regioselective glycosylation of 2-nitroglycals. ACS Catal. 2020, under minor revision. #

22. *Báti, G.; *He, J.-X.; **Pal, K. B.; Liu, X.-W. Stereo- and regioselective glycosylation with protection-less sugar derivatives: An alluring strategy to access glycans and natural products. Chem. Soc. Rev. 2019, 48, 4006-4018. #

23. Du, Y.; Zhang, K.; Si, Z.; Liu, Y.; Turvey, M. E.; Raju, C.; Keogh, D.; Ruan, L.; Jothy, S. L.; Reghu, S.; Marimuthu, K.; De, P. P.; Ng, O. T.; Mediavilla, J. R.; Kreiswirth, B. N.; Chi, Y. R.; Ren, J.; Tam, K. C.; Liu X.-W.; Duan, H.; Zhu, Y. Mu, Y.; Hammond, P. T.; Bazan, G. C.; Pethe, K.; Chan-Park, M. B. Enantiomeric glycosylated cationic block co-beta-peptides eradicate Staphylococcus aureus biofilms and antibiotic-tolerant persisters. Nat. Commun. 2019, 10, 4792. #

24. *Yao, H.; **William, R.; **Wang, S.; Guo, T.; Liu, X.-W. One-pot cascade transformation of glucal into structurally diverse drug-like scaffolds. Chem. Asian J. 2019, 14, 4024-4030. #

25. *Xu, Y.; Zhang, K.; Reghu, S.; **Lin, Y.; Chan-Park, M. B.; Liu, X.-W. Synthesis of antibacterial glycosylated polycaprolactones bearing imidazoliums with reduced hemolytic activity. Biomacromolecules 2019, 20, 949-958. #

26. *Das, M.; *Vu, M. D.; **Zhang, Q.; Liu, X.-W. Metal-free Visible Light Photoredox enables generation of carbyne equivalents via phosphonium ylides C-H activation. Chem. Sci. 2019, 10, 1687-1691. #

27. *Yao, H.; *Vu, M. D.; Liu, X.-W. Recent advances in reagent-controlled stereoselective/stereospecific glycosylation. Carbohydr. Res. 2019, 473, 72-81.

28. *Vu, M. D.; *Leng, W. L.; Hsu, H.-C.; Liu, X.-W. Alkene synthesis using phosphonium ylides as umpolung reagents. Asian J. Org. Chem. 2019, 8, 93-96. #

29. *Leng, W. L.; *Yao, H.; *He, J.-X.; Liu, X.-W. Venturing beyond donor-controlled glycosylation: new perspectives towards anomeric selectivity. Acc. Chem. Res. 2018, 51, 628-639. #

30. Zhao, S.; Huang, J.-J.; Sun, X.; Huang, X.; Fu, S.; Yang, L.; Liu, X.-W.; He, F.; Deng, Y. (1-Aryloxy-2-hydroxypropyl)-phenylpiperazine derivatives suppress candida albicans virulence by interfering with morphological transition. Microb. Biotechnol. 2018, 11, 1080-1089.

31. Low, Z. J.; Pang, L. M.; Ding, Y.; Cheang, Q. W.; **Le Mai Hoang, K.; Tran, H. T.; Li, J.; Liu, X.-W.; Kanagasundaram, Y.; Yang, L.; Liang, Z.-X. Identification of a biosynthetic gene cluster for the polyene macrolactam sceliphrolactam in a streptomyces strain isolated from mangrove sediment. Sci. Rep. 2018, 8, 1594. #

32. *Liao, H.; Ma, J.; *Yao, H.; Liu, X.-W. Recent progress of c-glycosylation methods in the total synthesis of natural products and pharmaceuticals. Org. Biomol. Chem. 2018, 16, 1791-1806. #

33. Mahadevegowda, S. H.; Hou, S.; Ma, J.; Keogh, D.; Zhang, J.; **Mallick, A.; Liu, X.-W.; Duan, H.; Chan-Park, M. B. Raman-encoded, multivalent glycan-nanoconjugates for traceable specific binding and killing of bacteria. Biomater. Sci. 2018, 6, 1339-1346. #

34. **Huang, N.; *Liao, H.; *Yao, H.; Xie, T.; Zhang, S.; Zou, K.†; Liu, X.-W. Diastereoselective synthesis of c-vinyl glycosides via gold(i)-catalyzed tandem 1,3-acyloxy migration/Ferrier rearrangement. Org. Lett. 2018, 20, 16-19. #

35. Fong, J.; Zhang, C.; Liang, R.; Boo, Z. Z.; Tan, S. K.; Nielsen, T. E.; Givskov, M.; Liu, X.-W., Bin, W.; Su H.; Yang, L. Combination therapy strategy of quorum quenching enzyme and quorum sensing inhibitor in suppressing multiple quorum sensing pathways of P. aeruginosa. Sci. Rep. 2018, 8, 1155. #

36. Vedachalam, S.; Murugesh, N.; Chakraborty, P.; Karvembu, R.; Liu, X.-W. NHC catalyzed enantioselective coates-claisen rearrangement: a rapid access to the dihydropyran core for oleuropein based secoiridoids. New J. Chem. 2018, 42, 1832-1839. #

37. **Mallick, A.; *Xu, Y.; **Lin, Y.; *He, J.-X.; Chan-Park, M. B.; Liu, X.-W. Oxadiazabicyclooctenone as a versatile monomer for the construction of pH sensitive functional polymers via ROMP. Polymer Chem. 2018, 9, 372-377. #

38. **Le Mai Hoang, K.; *He, J.-X.; *Báti, G.; Chan-Park, M. B.; Liu, X.-W. A minimalist approach to stereoselective glycosylation with unprotected donors. Nat. Commun. 2017, 8, 1146. #

39. Lv, X.; Cao, H.; Lin, B.; Wang, W.; Zhang, W.; Duan, Q.; Tao, Y.; Liu, X.-W.; Li, X. Synthesis of sialic acids, their derivatives, and analogs by using a whole-cell catalyst. Chem. Eur. J. 2017, 23, 15143-15149. #

40. *Vu, M. D.; *Das, M.; Liu, X.-W. Direct aldehyde Csp2-H functionalization through visible-light-mediated photoredox catalysis. Chem. Eur. J. 2017, 23, 15899-15902. #

41. *Yao, H.; Zhang, S.; *Leng, W. L.; **Leow, M. L.; **Xiang, S.; *He, J.-X.; *Liao, H.; **Le Mai Hoang, K.; Liu, X.-W. Catalyst-controlled stereoselective O-glycosylation: Pd(0) vs Pd(II). ACS Catalysis 2017, 7, 5456-5460. #

42. Hou, Z.; Shankar, Y. V.; Liu, Y.; **Ding, F.; Subramanion, J. L.; Ravikumar, V.; Zamudio-Vázquez, R.; Keogh, D.; Lim, H.; Tay, M. Y. F.; Bhattacharjya, S.; Rice, S. A.; Shi, J.; Duan, H.; Liu, X.-W.; Mu, Y.; Tan, N. S.; Tam, K. C.; Pethe, K.; Chan-Park, M. B. Nanoparticles of short cationic peptidopolysaccharide self-assembled by hydrogen bonding with antibacterial effect against multidrug-resistant bacteria. ACS Appl. Mater. Interfaces 2017, 9, 38288-38303. #

43. *Liao, H.; *Leng, W. L.; **Le Mai Hoang, Kim; *Yao, H.; *He, J.-X.; Voo, A. Y. H.; Liu, X.-W. Asymmetric syntheses of 8-oxabicyclo[3,2,1]octane and 11-oxatricyclo[5.3.1.0] undecane from glycals. Chem. Sci. 2017, 8, 6656-6661. #

44. *Leng, W. L.; *Liao, H.; *Yao, H.; Ang, Z.-E.; **Xiang, S.; Liu, X.-W. Palladium-catalyzed decarboxylative allylation/Wittig reaction: substrate-controlled synthesis of C-vinyl glycosides. Org. Lett. 2017, 19, 416-419. #

45. Zeng, J.; Sun, G.; Yao, W.; Zhu, Y.; Wang, R.; Cai, L.; Liu, K.; Zhang, Q.; Liu, X.-W.; Wan, Q. 3-Aminodeoxypyranoses in glycosylation: diversity-oriented synthesis and assembly in oligosaccharides. Angew. Chem. Int. Ed. 2017, 56, 5227-5231. #

46. **Wu, X.; *Tan, Y. J.; Toh, H. T.; Nguyen, L. H.; *Kho, S. H.; Chew, S. Y.; Yoon, H. S.; Liu, X.-W. Stimuli-responsive multifunctional glyconanoparticle platforms for targeted drug delivery and cancer cell imaging. Chem. Sci. 2017, 8, 3980-3988. #

47. *William, R.; *Leng, W. L.; **Wang, S.; Liu, X.-W. The first intermolecular interrupted imino-Nazarov reaction: expeditious access to carbocyclic nucleoside analogues. Chem. Sci. 2016, 7, 1100-1103. #

48. *Chai, H.; **Le Mai Hoang, K.; *Vu, M. D.; Pasunooti, K. K.; Liu, C.-F.; Liu, X.-W. N-Linked glycosyl auxiliary-mediated native chemical ligation on aspartic acid: application towards N-glycopeptide synthesis. Angew. Chem. Int. Ed. 2016, 55, 10363-10367. Highlighted by X-MOL. #

49. Xu, J.; Zhou, K.; Chen, F.; Chen, W.; Wei, X.; Liu, X.-W.; Liu, J. Natural integrated carbon architecture for rechargeable lithium-sulfur batteries. ACS Sustainable Chem. Eng. 2016, 4, 666-670.

50. *William, R.; **Wang, S.; **Mallick, A.; Liu, X.-W. Interrupting Nazarov reaction with different trapping modality: Utilizing potassium alkynyltrifluoroborate as a σ-nucleophile. Org. Lett. 2016, 18, 4458-4461. #

51. *Xiang, S.; *Le Mai Hoang, K.; *He, J.-X.; *Tan, Y. J.; Liu, X.-W. Reversing the stereoselectivity of a palladium-catalyzed O-glycosylation through an inner-sphere or outer-sphere pathway. Angew. Chem. Int. Ed. 2015, 54, 604-607. #

52. **Ding, F.; *William, R.; Kock, S. M.; **Leow, M. L.; Liu, X.-W. A concise route to the highly functionalized azetidine precursor: the enantioselective synthesis of penaresidin B. Chem. Commun. 2015, 51, 4639-4642. #

53. *Ji, L.; *Xiang, S.; *Leng, W. L.; *Le Mai Hoang, K.; Liu, X.-W. Palladium-catalyzed glycosylation: novel synthetic approach to diverse N-heterocyclic glycosides. Org. Lett. 2015, 17, 1357-1360. #

54. **Wu, J.; *Xiang, S.; **Zeng, J.; **Leow, M. L.; Liu, X.-W. Practical route to 2-quinolinones via a Pd-catalyzed C–H bond activation/C–C bond formation/cyclization cascade reaction. Org. Lett. 2015, 17, 222-225. Highlighted in Synfacts 2015, 11, 346. #

55. **Ma, J.; *Xiang, S.; Jiang, H.; Liu, X.-W. Palladium-catalyzed stereoselective C-glycosylation of glycals with sodium arylsulfinate. Eur. J. Org. Chem. 2015, 5, 949-952. #

56. **Wei, X.; **Liu, J.; Liu, X.-W. Ultrafine dice-like anatase TiO2 for highly efficient dye-sensitized solar cells. Sol. Energ. Mat. Sol. Cells 2015, 134, 133-139. #

57. **Liu, J.; **Wei, X.; Liu, X.-W. Two-dimensional wavelike spinel lithium titanate for fast lithium storage. Sci. Rep. 2015, 5, 9782. #

58. **Wu, J.; *Leng, W. L.; *Liao, H.; *Le Mai Hoang, K.; Liu, X.-W. Intramolecular C-N bond formation under metal-free conditions: Synthesis of indolizines. Chem. Asian J. 2015, 10, 853-856. #

59. **Wu, J.; *Le Mai Hoang, K.; **Leow, M. L.; Liu, X.-W. Pd-catalyzed cross-coupling of aromatic compounds with carboxylic acids via C-H bond activation. Org. Chem. Front. 2015, 2, 502-505. #

60. *Le Mai Hoang, K.; Liu, X.-W. The intriguing dual-directing effect of 2-cyanobenzyl ether for a highly stereospecific glycosylation reaction. Nat. Commun. 2014, 5, 5051. #

61. *William, R.; **Wang, S.; **Ding, F.; Arviana, E. N.; Liu, X.-W. Interrupted imino-Nazarov cyclization of 1-aminopentadienyl cation and related cascade process. Angew. Chem. Int. Ed. 2014, 53, 10742-10746. #

62. *Xiang, S.; He, J.-X.; *Tan, Y. J.; Liu, X.-W. Stereocontrolled O-glycosylation with palladium-catalyzed decarboxylative allylation. J. Org. Chem. 2014, 79, 11473-11482. #

63. Choi, B.-H.; Chattopadhaya, S.; Thanh, L. N.; Feng, L.; Nguyen, Q. T.; Lim, C. B.; Harikishore, A.; Nanga, R. P. R.; Bharatham, N.; Zhao, Y.; Liu, X.-W.; Yoon, H. S. Suprafenacine, an indazole-hydrazide agent, targets cancer cells through microtubule destabilization. PLoS ONE 2014, 9, e110955. #

64. *Bai, Y.; *Leng, W. L.; Li, Y.; Liu, X.-W. A highly efficient dual catalysis approach for C-glycosylation: addition of (O-azaaryl)carboxaldehyde to glycals. Chem. Commun. 2014, 50, 13391-13393. #

65. Tan, H. Y.; *Xiang, S.; *Leng, W. L.; Liu, X.-W. Regio- and stereoselective synthesis of β-keto functionalized C-glycosides via iron catalyzed Ferrier rearrangement reactions. RSC Adv. 2014, 4, 34816-34822. #

66. *Ge, X.; *Le Mai Hoang, K.; *Leow, M. L.; Liu, X.-W. Cascade reactions initiated by radical addition of tetrahydrofuran to β-bromonitrostyrenes. RSC Adv. 2014, 4, 45191-45197. #

67. Soehano, I.; Yang, L.; *Ding, F.; Sun, H.; Low, Z. J.; Liu, X.-W.; Liang, Z.-X. Insights into the programmed ketoreduction of partially reducing polyketide synthases: stereo- and substrate-specificity of the ketoreductase domain. Org. Biomol. Chem. 2014, 12, 8542-8549. #

68. **Ding, F.; *Leow, M. L.; **Ma, J.; *William, R.; *Liao, H.; Liu, X.-W. Collective synthesis of 4-hydroxy-2-pyridone alkaloids and their antiproliferation activities. Chem. Asian J. 2014, 9, 2548-2554. #

69. **Ding, F.; *Ji, L.; *William, R.; *Chai, H.; Liu, X.-W. Design and synthesis of multivalent neoglycoconjugates by click conjugations. Beilstein J. Org. Chem. 2014, 10, 1325-1332. #

70. *Bai, Y.; *Xiang, S.; *Leow, M. L.; Liu, X.-W. Dual-function Pd/NHC catalysis: tandem allylation-isomerization-conjugate addition that allows access to pyrroles, thiophenes and furans. Chem. Commun. 2014, 50, 6168-6170. #

71. *Cai, S.; *Zeng, J.; Li, Y.; Liu, X.-W. Polysubstituted pyrrole derivatives via 1,2-alkenyl migration of novel γ-amino-α,β-unsaturated aldehydes and α-diazocarbonyls. RSC Adv. 2014, 4, 7275-7278. #

72. *Zeng, J.; *Tan, Y. J.; **Ma, J.; *Leow, M. L.; Tirtorahardjo, D.; Liu, X.-W. Facile access to cis-2,6-disubstituted tetrahydropyrans by palladium-catalyzed decarboxylative allylation: Total syntheses of (±)-centrolobine and (+)-decytospolides A and B. Chem. Eur. J. 2014, 20, 405-409. #

73. **Ding, F.; *William, R.; *Leow, M. L.; *Chai, H.; Fong, J. Z. M.; Liu, X.-W. Directed orthometalation and the asymmetric total synthesis of N-deoxymilitarinone A and torrubiellone B. Org. Lett. 2014, 16, 26-29. #

74. *Xiang, S.; He, J.-X.; **Ma, J.; Liu, X.-W. One-pot synthesis of β-N-glycosyl imidazole analogues via a palladium-catalysed decarboxylative allylation. Chem. Commun. 2014, 50, 4222–4224. #

75. *Xiang, S.; **Lu, Z.; He, J.-X.; *Le Mai Hoang, K.; *Zeng, J.; Liu, X.-W. β-Type glycosidic bond formation by palladium-catalyzed decarboxylative allylation. Chem. Eur. J. 2013, 19, 14047-14051. #

76. Harikishore, A.; *Leow, M. L.; Niang, M.; Rajan, S.; **Pasunooti, K. K.; Preiser, P. R.; Liu, X.-W.; Yoon, H. S. Adamantyl derivative as a potent inhibitor of plasmodium FK506 binding protein 35. ACS Med. Chem. Lett. 2013, 4, 1097-1101.

77. *Wang, S.; *William, R.; Seah, K. K. G. E.; Liu, X.-W. Lewis acid–surfactant-combined catalyzed synthesis of 4-aminocyclopentenones from glycals in water. Green Chem. 2013, 15, 3180-3183. #

78. *Bai, Y.; *Le Mai Hoang, K.; *Liao, H.; Liu, X.-W. Oxidative Heck reaction of glycals and aryl hydrazines: A palladium-catalyzed C-glycosylation. J. Org. Chem. 2013, 78, 8821-8825. #

79. *Zeng, J.; **Ma, J.; *Xiang, S.; *Cai, S.; Liu, X.-W. Stereoselective β-C-glycosylation by a palladium-catalyzed decarboxylative allylation: Formal synthesis of aspergillide A. Angew. Chem. Int. Ed. 2013, 52, 5134-5137. Highlight in Synfacts 2013, 9, 870. #

80. *Le Mai Hoang, K.; *Bai, Y.; *Ge, X.; Liu, X.-W. Exploring the native chemical ligation concept for highly stereospecific glycosylation reactions. J. Org. Chem. 2013, 78, 5196-5204. #

81. *Leow, M. L.; Chin, H. L.; Yu, P. S.; **Pasunooti, K. K.; Tay, R. X.; Zhang, D.; Yoon, H. S.; Liu, X.-W. Benzofuran-based estrogen receptor α modulators as anti-cancer therapeutics: In silico and experimental studies. Curr. Med. Chem. 2013, 20, 2820-2837. #

82. *Ding, F.; *Cai, S.; *William, R.; Liu, X.-W. Pathways leading to 3-amino- and 3-nitro-2,3-dideoxy sugars: strategies and synthesis. RSC Adv. 2013, 3, 13594-13621. #

83. *Ding, F.; *William, R.; Liu, X.-W. Ferrier-type N-glycosylation: Synthesis of N-glycosides of enone sugars. J. Org. Chem. 2013, 78, 1293-1299. #

84. *Gorityala, B. K.; **Lu, Z.; *Leow, M. L.; *Ma, J.; Liu, X.-W. Design of a “turn-off/turn-on” biosensor: Understanding carbohydrate-lectin interactions for use in noncovalent drug delivery. J. Am. Chem. Soc. 2012, 134, 15229-15232. #

85. *Zeng, J.; *Tan, Y. J.; *Leow, M. L.; Liu, X.-W. Copper(II)/Iron(III) co-catalyzed intermolecular diamination of alkynes: Facile synthesis of imidazopyridines. Org. Lett. 2012, 14, 4386-4389. Highlight in Synfacts 2012, 8, 1300. #

86. *Ding, F.; *William, R.; Wang, F.; Liu, X.-W. Triflimide-catalyzed allyl-allyl cross-coupling: a metal-free allylic alkylation. Chem. Commun. 2012, 48, 8709-8711. Highlighted by Synfacts 2012, 8, 1142. #

87. Sun, H.; Ho, C.-L.; *Ding, F.; Soehano, I.; Liu, X.-W.; Liang, Z.-X. Synthesis of (R)-mellein by a partially reducing iterative polyketide synthase. J. Am. Chem. Soc. 2012, 134, 11924-11927. #

88. **Song, J.; Yang, H. B.; Wang, X.; Khoo, S. Y.; Wong, C. C., Liu, X.-W.; Li, C. M. Improved utilization of photogenerated charge using fluorine-doped tio2 hollow spheres scattering layer in dye-sensitized solar cells. ACS Appl. Mater. Interfaces 2012, 4, 3712-3717. #

89. **Maji, B.; *Ji, L.; *Wang, S.; *Vedachalam, S.; Ganguly, R.; Liu, X.-W. N-Heterocyclic carbene catalyzed homoenolate-addition reaction of enals and nitroalkenes: Asymmetric synthesis of 5-carbon-synthon δ-nitroester. Angew. Chem. Int. Ed. 2012, 51, 8276-8280. Highlighted by Organic-Chemistry Portal, July 22, 2013. #

90. Xiao, J.; Duong, H. M.; Liu, Y.; Shi, W.; *Ji, L.; Li, G.; Li, S.; Liu, X.-W.; Ma, J.; Wudl, F.; Zhang, Q. Synthesis and structure characterization of a stable nonatwistacene. Angew. Chem. Int. Ed. 2012, 51, 6094-6098. Highlight in Synfacts 2012, 5309-5319 by Prof. T. M. Swager. #

91. *Ding, F.; *William, R.; *Cai, S.; *Ma, J.; Liu, X.-W. Direct and stereoselective synthesis of 1,3-cis-3-arylsulphonaminodeoxydisaccharides and oligosaccharides. J. Org. Chem. 2012, 77, 5245-5254. #

92. *Liu, J.; Liu, X.-W. Two-dimensional nanoarchitecture for lithium storage. Adv. Mater. 2012, 24, 4097-4111. #

93. Han, N.; Liu, X.-W.; Mu, Y. Exploring the mechanism of zanamivir resistance in a neuraminidase mutant: A molecular dynamics study. PLoS ONE 2012, 7, e44057. #

94. *Vedachalam, S.; Tan, S. M.; Teo, H. P.; *Cai, S.; Liu, X.-W. N-heterocyclic carbene catalyzed c-glycosylation: A concise approach from Stetter reaction. Org. Lett. 2012, 14, 174-177. #

95. *Cai, S.; *Zeng, J.; *Bai, Y.; Liu, X.-W. Access to quinolines through gold-catalyzed intermolecular cycloaddition of 2-aminoaryl carbonyls and internal alkynes. J. Org. Chem. 2012, 77, 801-807. #

96. Xiao, J.; Liu, S.; Liu, Y.; *Ji, L.; Liu, X.-W.; Zhang, H.; Sun, X.; Zhang, Q. Synthesis, structure, and physical properties of 5,7,14,16-tetraphenyl-8:9,12:13-bisbenzo-hexatwistacene. Chem. Asian J. 2012, 7, 561-564. #

97. Jiao, Z..; **Song, J. L.; Sun, X.; Liu, X.-W.; Wang, J. M.; Ke, L.; Demir, H. V. A fast-switching light-writable and electric-erasable negative photoelectrochromic cell based on Prussian blue films. Sol. Energ. Mat. Sol. Cells. 2012, 98, 154-160. #

98. Jiao, Z.; Wang, J.; Ke, L.; Liu, X.-W.; Demir, H. V.; Yang, M. F.; Sun, X. W. Electrochromic properties of nanostructured tungsten trioxide (hydrate) films and their applications in a complementary electrochromic device. Electrochim. Acta. 2012, 63, 153-160. #

99. *Zeng, J.; *Bai, Y.; *Cai, S.; *Ma, J.; Liu, X.-W. Direct synthesis of pyrroles via a silver-promoted three-component reaction involving unusual imidazole ring opening. Chem. Commun. 2011, 47, 12855-12857. #

100. *Bai, Y.; *Zeng, J.; *Cai, S.; Liu, X.-W. Palladium-catalyzed direct cross-coupling reaction of glycals with activated alkenes. Org. Lett. 2011, 13, 4394-4397. #

101. *Xiang, S.; *Cai, S.; *Zeng, J.; Liu, X.-W. Regio- and stereoselective synthesis of 2-deoxy-C-aryl glycosides via palladium catalyzed decarboxylative reactions. Org. Lett. 2011, 13, 4608-4611. #

102. *Bai, Y.; *Leow, M. Li; *Zeng, J.; Liu, X.-W. Palladium catalyzed stereoselective C-glycosylation of glycals with enol triflates. Org. Lett. 2011, 13, 5648-5651. #

103. *Lorpitthaya, R.; **Suryawanshi, S. B.; *Wang, S.; *Pasunooti, K. K.; *Cai, S.; *Ma, J.; Liu, X.-W. Total synthesis of sialic acids by a sequential rhodium-catalyzed aziridination and Barbier allylation of D-glycal. Angew. Chem. Int. Ed. 2011, 50, 12054-12057. #

104. *Cai, S.; *Xiang, S.; *Zeng, J.; *Gorityala, B. K.; Liu, X.-W. Facile synthesis of carbohydrate-integrated isoxazolines through tandem [4+1] cycloaddition and rearrangement of 2-nitroglycals. Chem. Commun. 2011, 47, 8676-8678. #

105. *Song, J.; Yin, Z.; Yang, Z.; Amaladass, P.; Wu, S.; Ye, J.; Zhao, Y.; Deng W.-Q.; Zhang, H.; Liu, X.-W. Enhancement of photogenerated electron transport in dye-sensitized solar cells with introduction of a reduced graphene oxide-tio2 junction. Chem. Eur. J. 2011, 17, 10832-10837. #

106. Xiao, J.; Yin, Z.; Yang, B.; Liu, Y.; *Ji, L.; Guo, J.; Huang, L.; Liu, X.-W.; Yan, Q.; Zhang, H.; Zhang; Q. Preparation, characterization, physical properties, and photoconducting behaviour of anthracene derivative nanowires. Nanoscale 2011, 3, 4720-4723. #

107. **Maji, B.; *Vedachalam, S.; *Ge, X.; *Cai, S.; Liu, X.-W. N-Heterocyclic carbene-mediated oxidative esterification of aldehydes: Ester formation and mechanistic studies. J. Org. Chem. 2011, 76, 3016-3023. Featured Article. #

108. *Liu, J.; **Wei, X.; Wang, X.; Liu, X.-W. High-yield synthesis of ultrathin silica-based nanosheets and their superior catalytic activity in H2O2 decomposition. Chem. Commun. 2011, 47, 6135-6137. #

109. **Wei, X.; *Liu, J.; Chua, Y. Z.; *Song, J.; Liu, X.-W. Fabrication of O (dye)-terminated anatase TiO2 nanosheets for dye sensitized solar cells. Energy Environ. Sci. 2011, 4, 2054-2057. #

110. *Vedachalam, S.; *Choi, B.-H.; *Pasunooti, K. K.; Ching, K. M.; Lee, K.; Yoon, H. S.; Liu, X.-W. Glycosylated porphyrin derivatives and their photodynamic activity in cancer cells. Med. Chem. Commun. 2011, 2, 371-377. Highlighted as Hot Paper. #

111. *Ding, F.; *William, R.; *Wang, S.; *Gorityala, B. K.; Liu, X.-W. Ready access to 3-amino-2,3-dideoxysugars via regio- and stereo-selective tandem hydroamination-glycosylation of glycals. Org. Biomol. Chem. 2011, 9, 3929-3939. #

112. *Xiang, S.; *Ma, J.; *Gorityala, B. K.; Liu, X.-W. Stereoselective synthesis of β-N-glycosides through 2-deoxy-2-nitroglycal. Carbohydrate Res. 2011, 346, 2957-2959.

113. *Gorityala, B. K.; *Ma, J.; *Pasunooti, K. K.; *Cai, S.; Liu, X.-W. Green glycosylation promoted by reusable biomass carbonaceous solid acid: an easy access to β-stereoselective terpene galactosides. Green Chem. 2011, 13, 573-577. #

114. Lee, A. N.; Hartono, Y. D.; Sun, T.; *Leow, M. L.; Liu, X.-W.; Huang, X.; Zhang, D. Molecular dynamics studies of human receptor molecule in hemagglutinin of 1918 and 2009 H1N1 influenza viruses. J. Mol. Model 2011, 17, 1635-1641.

115. *Vedachalam, S.; Wong, Q.-L.; **Maji, B.; *Zeng, J.; *Ma, J.; Liu, X.-W. N-Heterocyclic carbene catalyzed intramolecular hydroacylation of activated alkynes: Synthesis of chromones. Adv. Synth. Cat. 2011, 353, 219-225. Highlighted by Synfacts 2011, 5, 0476-0476. #

116. *Cai, S.; *Gorityala, B. K.; *Ma, J.; *Leow, M. L.; Liu, X.-W. [3+2] Cycloaddition on carbohydrate templates: Stereoselective synthesis of pyrrolidines. Org. Lett. 2011, 13, 1072-1075. Highlighted by ACS Noteworthy Chemistry, March 14, 2011. #

117. Kyaw, A. K. K.; Sun X.; Zhao, J. L.; Wang, J. X.; Zhao, D. W.; Wei, X. F.; Liu, X.-W.; Demir, H. V.; Wu, T. Top-illuminated dye-sensitized solar cells with a room-temperature-processed ZnO photoanode on metal substrates and a Pt-coated Ga-doped ZnO counter electrode. J. Phys. D: Appl. Phys. 2011, 44, Article Number: 045102. #

118. *Pasunooti, K. K.; *Song, J.; *Chai, H.; Amaladass, P.; Deng, W.-Q.; Liu, X.-W. Synthesis, characterization and application of trans-D-B-A-porphyrin based dyes in dye-sensitized solar cells. J. Photochem. Photobiol., A 2011, 218, 219-225. #

119. Wei, L.; Jiang, P.; Xu, W.; Li, H.; Zhang, H.; Yan, L.; Chan-Park, M. B.; Liu, X.-W.; Tang, K.; Mu Y.; Konstantin P. The molecular basis of distinct aggregation pathways of islet amyloid polypeptide. J. Biol. Chem. 2011, 286, 6291-6300. #

120. *Ding, F.; *William, R.; Wang, F.; *Ma, J.; *Ji, L.; Liu, X.-W. A short and highly efficient synthesis of L-ristosamine and L-epi-daunosamine glycosides. Org. Lett. 2011, 13, 652-655. #

121. Wang, X.; *Song, J.; Yip, C. H.; Wong, C. C.; Liu, X.-W. Influence of TiF4 treatment on tio2 photoanode in dye sensitized solar cells. Nanosci. Nanotechnol. Lett. 2011, 3, 191-194.

122. Amaladass, P.; *Pasunooti, K. K.; Png, Z.; Liu, X.-W. Facile synthesis and characterization of new polymerizable conjugated 2,5-di(selenophen-2-yl)pyrroles and 2,5-difuranylpyrroles. Tetrahedron Lett. 2011, 52, 711-714.

123. *Zeng, J.; *Vedachalam, S.; *Xiang, S.; Liu, X.-W. Direct C-Glycosylation of organotrifluoroborates with glycosyl fluorides and its application to the total synthesis of (+)-varitriol. Org. Lett. 2011, 13, 42-45. Highlighted by Organic-Chemistry Portal, January 16, 2012. #

124. *Song, J.; Amaladass, P.; Wen, S.-H.; *Pasunooti, K. K.; Li, A.; Yu, Y.-L.; Wang, X.; Deng, W.-Q.; Liu, X.-W. Aryl/hetero-arylethyne bridged dyes: the effect of planar p-bridge on the performance of dye-sensitized solar cells. New J. Chem. 2011, 35, 127-136. #

125. *Liu, J.; Chen, J. S.; **Wei, X.; Lou, X. W.; Liu, X.-W. Sandwich-like, stacked ultrathin titanate nanosheets for ultrafast lithium storage. Adv. Mater. 2011, 23, 998-1002. Highlighted by Wiley-VCH ChemistryViews, 04 January, 2011. Highlighted by RSC Nanowerk, 2011. #

126. *Pasunooti, K. K.; *Chai, H.; Jensen, C. N.; *Gorityala, B. K.; *Wang, S.; Liu, X.-W. A microwave-assisted, copper-catalyzed three-component synthesis of dihydropyrimidinones under mild conditions. Tetrahedron Lett. 2011, 52, 80-84.

127. Kristian, N.; Yu, Y.; Lee, J.-M.; Liu, X.-W.; Wang, X. Synthesis and characterization of CocorePtshell electrocatalyst prepared by spontaneous replacement reaction for oxygen reduction reaction. Electrochim. Acta 2010, 56, 1000-1007. #

128. *Liu, J.; **Wei, X.; Yu, Y.; Wang, X.; Deng, W.-Q.; Liu, X.-W.Nanoreactors’ for photocatalytic H2 evolution in oil-water biphase systems. Phys. Chem. Chem. Phys. 2010, 12, 14449-14451. Highlighted by NPG (Nature Publishing Group) Asia Materials, January 31, 2011. #

129. Liang, R.; **Pasunooti, K. K.; Li, F.; Liu, X.-W.; Liu, C.-F. Synthesis of K48-linked diubiquitin using dual native chemical ligation at lysine. Chem. Commun. 2010, 46, 7199-7201. Highlighted by Chemical & Engineering News, Oct. 11, 2010, PP36-37. Also highlighted by Ronald T. Raines, Angew. Chem. Int. Ed. 2010, 49, 9042. Chemical Year in Review, Dec. 20, 2010, PP13-17 (Chemical & Engineering News). #

130. *Bai, Y.; *Zeng, J.; *Ma, J.; *Gorityala, B. K.; Liu, X.-W. Quick access to druglike heterocycles: Facile silver-catalyzed one-pot multicomponent synthesis of aminoindolizines. J. Comb. Chem. 2010, 12, 696-699.

131. *Pasunooti, K. K.; Jensen, C. N.; *Chai, H.; *Leow, M. L.; Zhang, D.; Liu, X.-W. Microwave-assisted copper(II)-catalyzed one-pot four-component synthesis of multifunctionalized dihydropyrindines. J. Comb. Chem. 2010, 12, 577-581.

132. *Ding, F.; *William, R.; *Gorityala, B. K.; *Ma, J.; *Wang, S.; Liu, X.-W. A mild and efficient synthetic protocol for Ferrier azaglycosylation promoted by ZnCl2/Al2O3. Tetrahedron Lett. 2010, 51, 3146-3148. Highlighted by Synfacts 2010, 8, 0965-0965.

133. *Ma, J.; Ng, S.; Yong, Y.; Luo, X.-Z.; Wang, X.; Liu, X.-W. Recyclable sulfonated amorphous carbon catalyzed Friedel-Crafts alkylation of indoles with α,β-unsaturated carbonyl compounds in water. Chem. Asian J. 2010, 5, 778-782. Highlighted by Synfacts 2010, 7, 0837-0837. #

134. *Vedachalam, S.; *Zeng, J.; *Gorityala, B. K.; Antonio, M.; Liu, X.-W. N-Heterocyclic carbene-catalyzed intramolecular aldehyde-nitrile cross coupling: An easy access to 3-aminochromones. Org. Lett. 2010, 12, 352-355. Highlighted by Synfacts 2010, 3, 0352-0352. #

135. *Gorityala, B. K.; *Ma, J.; Wang, X.; Chen, P.; Liu, X.-W. Carbohydrate functionalized carbon nanotubes and their applications. Chem. Soc. Rev. 2010, 39, 2925-2934. Invited review. #

136. *Liu, J.; **Wei, X.; Yu, Y.; *Song, J.; Wang, X.; **Li, A.; Liu, X.-W.; Deng, W.-Q. Uniform core-shell titanium phosphate nanospheres with orderly open nanopores: a highly active Brønsted acid catalyst. Chem. Commun. 2010, 46, 1670-1672. #

137. *Ma, J.; Zhao, Y.; Ng, S.; Zhang, J.; *Zeng, J.; Than, A.; Chen, P.; Liu, X.-W. Sugar-based synthesis of tamiflu and its inhibitory effects on cell secretion. Chem. Eur. J. 2010, 16, 4533-4540. #

138. Wang, Y.; Nguyen, T. S.; Liu, X.-W.; Wang, X. Novel palladium-lead (Pd-Pb/C) bimetallic catalysts for electrooxidation of ethanol in alkaline media. J. Power Sources 2010, 195, 2619-2622. #

139. *Lorpitthaya, R.; Xie, Z.-Z.; Sophy, K. B.; Kuo, J.-L.; Liu, X.-W. Mechanistic insights into the substrate-controlled stereochemistry of glycals in one-pot rhodium-catalyzed aziridination and aziridine ring opening. Chem. Eur. J. 2010, 16, 588-594. #

140. Chen, J.; Zhao, D. W.; *Song, J. L.; Sun, X. W.; Deng, W.-Q.; Liu, X.-W.; Lei, W. Directly assembled CdSe quantum dots on TiO2 in aqueous solution by adjusting pH value for quantum dot sensitized solar cells. Electrochem. Commun. 2009, 11, 2265-2267. #

141. Liang, R.; *Pasunooti, K. K.; Li, F.; Liu, X.-W.; Liu, C.-F. Dual native chemical ligation at lysine. J. Am. Chem. Soc. 2009, 131, 13592-13593. Highlighted by Chemical & Engineering News, 21 Sept. 2009, P35. #

142. *Pasunooti, K. K.; Liang, R.; *Vedachalam, S.; *Gorityala, B. K.; Liu, C.-F.; Liu, X.-W. Synthesis of 4-mercapto-L-lysine derivatives: potential building blocks for sequential native chemical ligation. Bioorg. Med. Chem. Lett. 2009, 19, 6268-6271.

143. Yu, Y.; Hu, Y.; Liu, X.-W.; Deng, W.-Q.; Wang, X. The study of Pt@Au electrocatalyst based on Cu underpotential deposition and Pt redox replacement. Electrochim. Acta 2009, 54, 3092-3097. #

144. Sudibya, H. G.; *Ma, J.; Dong, X.; Ng, S.; Li, L.-J.; Liu, X.-W.; Chen P. Interfacing glycosylated carbon-nanotube-network devices with living cells to detect dynamic secretion of biomolecules. Angew. Chem. Int. Ed. 2009, 48, 2723-2726. #

145. *Lorpitthaya, R.; Sophy, K. B.; Kuo, J.-L.; Liu, X.-W. Highly stereoselective synthesis of aminoglycosides via rhodium-catalyzed and substrate-controlled aziridination of glycals. Org. Biomol. Chem. 2009, 7, 1284-1287. #

146. *Gorityala, B. K.; *Cai, S.; *Ma, J.; Liu, X.-W. (S)-Camphorsulfonic acid catalyzed highly stereoselective synthesis of pseudoglycosides. Bioorg. Med. Chem. Lett. 2009, 19, 3093-3095. Highlighted in ChemInform Abstract.

147. *Gorityala, B. K.; *Cai, S.; *Lorpitthaya, R.; *Ma, J.; *Pasunooti, K. K.; Liu, X.-W. A convenient synthesis of pseudoglycosides via a Ferrier-type rearrangement using metal-free H3PO4 catalyst. Tetrahedron Lett. 2009, 50, 676-679.

148. *Gorityala, B. K.; *Lorpitthaya, R.; *Bai, Y.; Liu, X.-W. ZnCl2/alumina impregnation catalyzed Ferrier rearrangement: an expedient synthesis of pseudoglycosides. Tetrahedron 2009, 65, 5844-5848. Highlighted in ChemInform Abstract. #

149. Wang, Y.; Deng, W.-Q.; Liu, X.-W.; Wang, S.; Wang, X. Electrochemical properties of ball-milled LaMg12-Ni composites containing carbon nanotubes. Int. J. Hydrogen Energy 2009, 34, 1444-1449. #

150. *Pasunooti, K. K.; *Leow, M. L.; *Vedachalam, S.; *Gorityala, B. K.; Liu, X.-W. A general and mild copper-catalyzed three-component synthesis of protected homoallyl amines. Tetrahedron Lett. 2009, 50, 2979-2981. Highlighted in ChemInform Abstract.

151. Wang, Y; Deng, W.-Q.; Liu, X.-W.; Wang, X. Electrochemical hydrogen storage properties of ball-milled multi-wall carbon nanotubes. Int. J. Hydrogen Energy 2009, 34, 1437-1443. #

152. Kristan, N.; Yu, Y.; Gunawan, P.; Xu, R.; Deng, W.-Q.; Liu, X.-W.; Wang, X. Controlled synthesis of Pt-decorated Au nanostructure and its promoted activity toward formic acid electro-Oxidation. Electrochim. Acta 2009, 54, 4916-4924. #

153. Ye, Y.; Zhang, M.; Liu, H.; Liu, X.-W.; Zhao, J. Theoretical investigation on the oligothienoacenes under the influence of external electric field. J. Phys. Chem. Solids 2008, 69, 2615-2621.

154. Liu, X.-W.; **Le, T. N.; Lu, Y.; Xiao, Y.; *Ma, J.; Li, X. An efficient synthesis of chiral phosphinyl oxide pyrrolidines and their application to asymmetric direct aldol reactions. Org. Biomol. Chem. 2008, 6, 3997-4003. Highlighted in ChemInform Abstract. #

155. Liu, X.-W.; *Ma, J.; Colson, A.-O.; Doersen, D. C.; Ebetino, F. H. Synthesis and biological activities of novel peptide mimetics as melanocortin receptor agonists. Bioorg. Med. Chem. Lett. 2008, 18, 1223-1228.

156. *Lorpitthaya, R.; Xie, Z.-Z.; Kuo, J.-L.; Liu, X.-W. Stereocontrolled intramolecular aziridination of glycals: Ready access to aminoglycosides and mechanistic insights from DFT studies. Chem. Eur. J. 2008, 14, 1561-1570. #

157. Cheng, X.-M.; Liu, X.-W. Microwave-enhanced one-pot synthesis of diversified 3-acyl-5-hydroxybenzofurans. J. Comb. Chem. 2007, 9, 906-908.

158. Tully, S. E.; Mabon, R.; Gama, C. I.; Tsai, S. M.; Liu, X.-W.; Linda C. H.-W. A chondroitin sulfate small molecule that stimulates neuronal growth. J. Am. Chem. Soc. 2004, 126, 7736-7737. #

159. Liu, X.-W.; Hu, X. E.; Tian, X.; Mazur, A.; Ebetino, F. H. Enantioselective synthesis of phosphinyl peptidomimetics via an asymmetric Michael reaction of phosphinic acids with acrylate derivatives. J. Organomet. Chem. 2002, 646, 212-222. #

160. Ebetino, F.H.; Soper, D. L.; Dirr, M. J.; Lundy, M. W.; Mieling, G.; Wos, J. A.; deLong, M. A.; Liu, X.-W. Phosphorus, Sulfur, Silicon and Relat. Elem. 2002, 177, 1725-1729.

161. Kende, A. S.; Dong, H.-Q.; Liu, X.-W.; Ebetino, F. H. A useful synthesis of the Phe-Arg phosphinic acid dipeptide isostere. Tetrahedron Lett. 2002, 43, 4973-4976.

162. Ebetino, F. H.; Rogers, M.; Dunford, J.; Liu, X.-W.; Phipps, R.; Russell, R. G. G.; Barnett, B.; Correa, P. Modeling of bisphosphonate binding to farnesyl diphosphate synthase. Bone 2002, 30, 40S. #

163. Liu, X.-W.; Li, Z.; McKenna, C. E. Synthetic and theoretical investigations of some sulfur-containing phosphonoformate derivatives. Phosphorus, Sulfur, Silicon and Relat. Elem. 1999, 147, 1041.

 

Book Chapters

1. *Leng, W. L.; *He, J.-X.; *Yao, H.; Liu, X.-W. Methodologies in Chemical Syntheses of Carbohydrates, Chapter 2 in book Synthetic Glycomes, Royal Society of Chemistry, 2018. (e-proof has been done, print in May 2019)

2. **Le Mai Hoang, K.; *Leng, W. L.; *Tan, Y. J.; Liu, X.-W. Stereoselective C-Glycosylation from Glycal Scaffolds, Chapter 7 in book Selective Glycosylations – Synthetic Methods and Catalysts, pp137-153, Wiley-VCH, 2017.

 

Conference Papers

1. Liu, X.-W. Glycosciences: The next biomolecular frontiers. ANNUM VI (Asian network for natural and unnatural materials) conference, Gifu, Japan, 27-28 July 2018.

2. *Chai, H.; **Le Mai Hoang, K.; Liu, X.-W. Dual glycosylation: a minimalist approach for oligosaccharide synthesis. The 29th International Carbohydrate Symposium, Lisbon, Portugal, 15-19th July, 2018.

3. *He, J.-X.; **Le Mai Hoang, K.; *Kho, S. H.; Liu, X.-W. Biohybrid peptidoglycan oligomers that incorporate into bacterial cell walls. The 11th International Symposium on Glycosyltransferases, Qingdao, China, 19-23 June, 2018.

4. Liu, X.-W. Advanced glycosylation methods that allows easy access to complex glycoconjugates. Synthetic Biology International Meeting, Wuhan, China, 21-22 May, 2018.

5. *He, J.-X.; **Le Mai Hoang, K.; *Xu, Y.; Liu, X.-W. Tailor-made peptidoglycans and glycoconjugates for antimicrobial research. 1st National Conference of Signal Communication and Pathogenesis in Microbes, Guangzhou, China, 1-4 December, 2017.

6. *He, J.-X.; *Bati, G.; *Chai, H.; Liu, X.-W. Tailor-made peptidoglycans and glycoconjugates for antimicrobial research. The Joint Meeting of 11th International Symposium on Integrated Synthesis (ISONIS-11) and 3rd International Symposium on Middle Molecular Strategy (3rd ISMMS), Osaka, Japan, 16-18 November, 2017.

7. Liu, X.-W. Glycosylation in carbohydrate synthesis and glycoprotein synthesis. 13th Midwest Carbohydrate and Glycobiology Symposium, Madison, WI, USA, 22-23 September, 2017.

8. Liu, X.-W. Antimicrobial peptides, glycopeptides and peptidoglycans. The 3rd Glycobiology World Congress, London, UK, 26-28 June, 2017.

9. Liu, X.-W. Synthesis of antimicrobial peptides, glycopeptides and peptidoglycans. The 2st Symposium of Carbohydrate Synthesis (首届糖合成化学高峰论坛), Jinan, China, 15-16 May, 2017.

10. **Le Mai Hoang, K.; *He, J.-X.; *Leng, W. L.; *Chai, H.; Liu, X.-W. Synthesis of antimicrobial peptides, glycopeptides and peptidoglycans. International Conference on Cellular & Molecular Bioengineering (ICCMB4), Singapore, 4-6 January, 2017.

11. *Chai, H.; **Le Mai Hoang, K.; Liu, X.-W. Dual Native chemical ligation: New methods for peptide and glycopeptide synthesis. The 14th International Symposium for Chinese Organic Chemists (ISCOC) and the 11th International Symposium for Chinese Inorganic Chemists (ISCIC), Singapore, 8-10 December, 2016.

12. *Chai, H.; *Leng, W. L.; **Le Mai Hoang, K.; Liu, X.-W. Dual native chemical ligation: New methods for peptide and glycopeptide synthesis. P2S2 Symposium, Singapore, 8-9 December, 2016.

13. *Chai, H.; **Le Mai Hoang, K.; Liu, X.-W. Quick assembly of glycosides and glycoproteins: General tactics and new glycosylation methods. The 28th International Carbohydrate Symposium, New Orleans, USA, 17-22 July, 2016.

14. **Le Mai Hoang, K.; Liu, X.-W. Glycosciences: from synthetic methods to glycobiology. 6th ICBE-International Conference on Biomolecular Engineering, Singapore, 5-7 January, 2016.

15. Liu, X.-W.; *Le Mai Hoang, K.; *Xiang, S.; **Gorityala, B. K. Exploring and exploiting carbohydrate-lectin interactions. The 2015 PacifiChem, Hawaii, 15-20 December, 2015.

16. *Le Mai Hoang, K.; *Xiang, S.; Liu, X.-W. Acceptor-controlled stereoselective glycosylation. The 1st Symposium of Carbohydrate Synthesis (首届糖合成化学高峰论坛), Nanchang, China, 10-11 April, 2015.

17. **Ma, J.; **Lu, Z.; **Gorityala, B. K.; Liu, X.-W. New glycosylation methods & new glycosylated nanodevice interfacing with living cells. 8th Singapore International Chemistry Conference, U-Town, Singapore, 14-17 December 2014.

18. Liu, X.-W.; *Le Mai Hoang, K.; *Xiang, S. The intriguing dual-directing effect of 2-cyanobenzyl ether for highly stereospecific glycosylation reaction. ICCEOCA-9/NICCEOCA-5, Petaling Jaya, Malaysia, 1-4 December, 2014.

19. Liu, X.-W.; *Le Mai Hoang, K.; *Xiang, S.; **Gorityala, B. K. New glycosylation methods & new glycosylated nanodevice interfacing with living cells. Society for Glycobiology (SFG) & Japanese Society of Carbohydrate Research (JSCR) Joint Meeting, Honolulu, Hawaii, 16-19 November, 2014.

20. Liu, X.-W.; *Le Mai Hoang, K.; **Gorityala, B. K. Efficient synthesis of oligosaccharides and biosensors based on carbohydrate-lectin interactions. Symposium on Glycobiology & Glycobiotechnology, Xi An, China, 16-19 July, 2014.

21. Liu, X.-W.; *Le Mai Hoang, K.; *Xiang, S.; **Gorityala, B. K. New glycosylation methods and new glycosylated nanodevices interfacing with living cells. The 15th Tetrahedron Symposium Asia, Singapore Expo, Singapore, 28-31 October, 2014.

22. Liu, X.-W.; *Le Mai Hoang, K.; **Gorityala, B. K.; **Ma, J. Our recent progress on new glycosylation methods and new glycosylated nanodevice interfacing with living cells. The 5th International Conference on the Development of Biomedical Engineering, Ho Chi Minh City, Vietnam,16-18 June, 2014.

23. Liu, X.-W.; **Lu, Z.; **Gorityala, B. K.; **Ma, J. Stereoselective glycosylation and its use in the synthesis of carbohydrates and natural products. 2014 Canadian Society for Chemistry (CSC) Conference, Vancouver, Canada, 1-5 June, 2014.

24. Liu, X.-W.; *Le Mai Hoang, K.; **Gorityala, B. K.; **Ma, J. Interfacing glycosylated nanodevice with living cells: from biosensing to drug delivery. Asia-Canada Glycoscience Meeting, Vancouver, Canada, 31 May – 1 June, 2014.

25. Liu, X.-W.; *Tan, Y. J.; **Ma, J. Glycosciences: From synthetic methods to glycobiology. Singapore – South Korea Symposium on Glycomics, BioProcessing Institute, A*STAR, Singapore, 13 February, 2014.

26. Liu, X.-W. Glycosciences: From synthetic methods to glycobiology. Gordon Conference, Mt Snow, Vermont, USA, 16-21 June, 2013.

27. **Lorpitthaya, R.; *Xiang, S.; *Ding, F.; *Zeng, J.; **Gorityala, B. K.; *Leow M. L.; Liu, X.-W. Glycosciences: From synthetic methods to glycobiology. 7th Glycan Forum Berlin, Germany, 20-22 March, 2013

28. **Lorpitthaya, R.; **Ma, J.; *Zeng, J.; *Ding, F.; *Gorityala, B. K.; *Leow M. L.; Liu, X.-W. Stereoselective synthesis of carbohydrates and natural products via facial control. 12th ISCOC and 9th ISCIC, Lanzhou, Gansu, China, 19–22 August, 2012.

29. **Ma, J.; **Lorpitthaya, R.; *Zeng, J.; *Ding, F.; *Gorityala, B. K.; *Leow M. L.; Liu, X.-W.# Stereoselective glycosylation and its use in the synthesis of carbohydrates and natural products. 26th international Carbohydrate Symposium, Madrid, Spain, 22-27 July, 2012.

30. **Ma, J.; **Lorpitthaya, R.; *Leow M. L.; *Zeng, J.; Liu, X.-W. Stereoselective glycosylation and its use in the synthesis of carbohydrates and natural products. 28th Chinese Chemical Society Conference, Chengdu, China, 13-16 April, 2012.

31. Liu, X.-W. Direct and stereoselective synthesis of a-linked 1,3-cis-3-aminodeoxyglycosides. The 6th International Conference on Cutting-Edge Organic Chemistry in Asia (ICCEOCA-6), Hong Kong, 11-15 December, 2011.

32. *Zeng, J.; Liu, X.-W. Facile synthesis of imidazopyridines via copper (II) and iron (III) Co-catalyzed intermolecular diamination of alkynes. Green Chemistry 2011 Innovations, Melbourne, 4-7 December, 2011.

33. *Wang, S.; Liu, X.-W. Green synthesis of cyclopentenones from glycals. Green Chemistry 2011 Innovations, Melbourne, 4-7 December, 2011.

34. *Cai, S.; Liu, X.-W. Carbohydrate-integrated isoxazolines through tandem [4 + 1] cycloaddition and rearrangement of 2-nitroglycals and sulphur ylides. Green Chemistry 2011 Innovations, Melbourne, 4-7 December, 2011.

35. *Cai, S.; *Gorityala, B. K.; *Ma, J.; *Leow M. L.; Liu, X.-W. [3+2] Cycloaddition on carbohydrate templates: Stereoselective synthesis of pyrrolidines. Perch-CIC Congress VII, Pattaya, Thailand, 4-7 May, 2011.

36. *Vedachalam, S.; Liu, X.-W. N-Heterocyclic carbene catalyzed chromone synthesis. 241st ACS National Meeting, Anaheim, CA, USA, 27-31 Mar, 2011.

37. *Gorityala, B. K.; Liu, X.-W. Glycosylation of unprotected and unactivated sugars. The 2010 PacifiChem, Honolulu, Hawaii, USA, 15-20 December, 2010.

38. *Pasunooti, K. K.; Liu, X.-W. Synthesis of K48-linked diubiquitin using dual native chemical ligation at photo labile group protected lysine. The 2010 PacifiChem, Honolulu, Hawaii, USA, 15-20 December, 2010.

39. *Vedachalam, S.; Liu, X.-W. N-Heterocyclic carbene catalyzed intramolecular aldehyde nitrile cross coupling: an easy access to 3-aminochromones. 6th Asian-European Symposium, Singapore, 7-9 June, 2010.

40. *Gorityala, B. K.; *Le Mai Hoang, K.; Yin, G.; Liu, X.-W. A novel approach towards the stereoselective glycoside bond formation. 6th Asian-European Symposium, Singapore, 7-9 June, 2010.

41. *Song, J.; Lim, B.; *Liu, J.; Deng, W.; Liu, X.-W. Hollow SnO2 light-scattering layer used for dye-sensitized solar cells. 6th Asian-European Symposium, Singapore, 7-9 June, 2010.

42. *Ding, F.; William, R.; Liu, X.-W. A facile and efficient one-pot synthesis of 3-amino-2,3-dideoxysugars. 6th Asian-European Symposium, Singapore, 7-9 June, 2010.

43. *Liu, J.; Chen, J.; **Wei, X.; Lou, X.-W.; Liu, X.-W. Facile large-scale fabrication of single-molecular-layer titania nanoslices with superior lithium storage capability. 6th Asian-European Symposium, Singapore, 7-9 June, 2010.

44. *Pasunooti, K. K.; Yang, R.; Li, F.; Liu, C.-F.; Liu, X.-W. Synthesis of K48-linked diubiquitin using dual native chemical ligation at lysine. 6th Asian-European Symposium, Singapore, 7-9 June, 2010.

45. *Wang, S.; *Lorpitthaya, R.; *Pasunooti, K. K.; Liu, X.-W. C-Aminoglycosylation via Barbier-type allylation of glycal: An approach to sialic acids (Neu5Ac). 6th Asian-European Symposium, Singapore, 7-9 June, 2010.

46. *Ma, J.; Ng, S.; *Zeng, J.; Liu, X.-W. Sugar-based synthesis of tamiflu and its inhibitory effects on cell secretion. 6th Asian-European Symposium, Singapore, 7-9 June, 2010.

47. *Zeng, J.; Bai, Y.; Liu, X.-W. Quick access to polyfunctionalized pyrroles and indolizines through silver-catalyzed one-pot multicomponent reaction. 6th Asian-European Symposium, Singapore, 7-9 June, 2010.

48. **Thanh, L. N.; Luo, X.; Liu, X.-W. Design and synthesis of new therapeutic agents for cancers. 27th CCS meeting, Xiamen, China, 19-23 June, 2010.

49. *Vedachalam, S.; Liu, X.-W. N-Heterocyclic carbene catalyzed intramolecular aldehyde nitrile cross coupling: An easy access to 3-aminochromones. Kyushu-CBC Joint Symposium, 28 January, 2010.

50. Liu, X.-W.; *Lorpitthaya, R.; *Wang, S.; *Pasunooti, K. K.; Luo, X. Synthetic study of unexpected C-aminoglycosylation via Barbier-Grignard type allylation/propargylation of glycal: An approach to sialic acids. The 4th International Conference on Cutting-Edge Organic Chemistry in Asia (ICCEOCA-4), Bangkok, Thailand, 29 November-3 December, 2009.

51. Liu, X.-W. Conversion of glucose and cellulose to DMF, a potential additive in gasoline. 1st Annual Workshop on Energy Research, Organized by ERI@N and NSWU, 6-7 August, 2009.

52. Liu, X.-W.; Yin, G. Biomass-derived gasoline additive. 1st Annual Workshop on Energy Research, Organized by ERI@N, 2-4 June 2009.

53. *Lorpitthaya, R.; Liu, X.-W. One-pot rhodium-catalyzed aziridination and ring-opening of glycal: A direct access to 2-amino sugars and its application to synthesis of sialic acids. 238th ACS National Meeting, Washington, DC, 16-20 August, 2009.

54. *Ma, J.; Liu, X.-W. Carbohydrate coating of carbon nanotubes for detection of cell secretion. 238th ACS National Meeting, Washington, DC, 16-20 August, 2009.

55. Liu, X.-W. Design and synthesis of new therapeutic agents for cancers. Combinatorial Chemistry and Chemical Biology toward a New Paradigm for Drug Discovery (CCCB), and 28th Conference on Combinatorial Chemistry, Osaka, Japan (JCCF28), 24-25 September, 2009.

56. Liu, X.-W. Synthesis of sugars and other neuritogenic molecules. 2nd UK-Singapore Symposium – Contemporary Organic Synthesis, Methods and Techniques, Biopolis, Singapore, 15 February, 2008.

57. Liu, X.-W. Sugars in organic synthesis and chemical biology. International Symposium on Catalysis and Fine Chemicals 2017, Nanyang Technological University, Singapore, 17-21 December 2007.

58. *Lorpitthaya, R.; Liu, X.-W. Intramolecular Rh-catalyzed aziridination of glycals: A novel direct access to aminoglycosides. PERCH-CIC Congress V, Pattaya city, Chonburi, Thailand, 6-9 May, 2007.

59. Liu, X.-W. Synthetic study of chondoitin sulfate small molecules that stimulate neuronal outgrowth. First International Conference of Cutting-Edge Organic Chemistry, Naha-city, Okinawa, Japan, 16-20 October, 2006.

60. Tully, S. E.; Mabon, R.; Liu, X.-W.; Gama, C.; Tsai, S. M.; Hsieh-Wilson, L. C. A chondroitin sulfate small molecule that stimulates neuronal growth. 228th ACS Meeting, Philadephia, Pennsylvania, 22-26 August, 2004.

61. Ebetino, F. H.; Soper, D. L.; Dirr, M. J.; Lundy, M. W.; Mieling, G.; Liu, X.-W.; Wos, J. A.; deLong, M. A. The rational design and utility of drugs with phosphonic/phinic acids, from enzyme inhibitors to bioisosteric receptors agonists. Ninth Workshop on Cell Biology of bone and Cartilage in Health and Disease, Davos, Switzerland, 16-19 March, 2002.

62. Ebetino, F. H.; Liu, X.-W.; Russell, R.G.G.; Rogers, M.; Mieling, G.; Phipps, R.; Mangood, A.; Mangood, E.; Nancollas, G. New developments in bisphosphonate research: Improving our understanding of their differences mechanistically. Sixth Workshop on Bisphosphonates – From the Laboratory to the Patients, Davos, Switzerland, 20-22 March, 2002.

63. Ebetino, F. H.; Liu, X.-W.; Nancollas, G. Rogers, M. New developments in bisphosphonates for osteoporosis. 223th ACS Meeting, Orlando, Florida, 7-11 Apr, 2002.

64. Liu, X.-W.; Ebetino, F. H. Enantioselective synthesis of phosphino peptidomimetics via asymmetric michael reaction of phosphinic acids with acrylate derivatives. 37th ACS Western Regional Meeting, Santa Barbara, California, 30 October, 2001.

65. Ebetino, F. H.; Liu, X.-W.; Soper, D. L.; Dirr, M. J.; Lundy, M. W.; Wos, J. A.; deLong, M. A. The rational design and utility of drugs with phosphonic/phinic acids, from enzyme inhibitors to receptor agonist bioisosteres. XVth International Conference on Phosphorus Chemistry, Sendai, Japan, 29 July – 3 August, 2001.

66. McKenna, C. E.; Liu, X.-W. Bisphosphonates in medicinal chemistry-past and prologue. 35th ACS Western Regional Meeting, Ontario, California, 6-8 October, 1999.

67. Liu, X.-W.; Li, Z.; McKenna, C. E. Lipophilic derivatives of PFA and TPFA. 217th ACS Meeting, Anaheim, California, 21-25 March, 1999.

68. Li, Z.; Liu, X.-W.; McKenna, C. E. The preparation of sulfur-containing phosphonoformate derivatives. XIVth International Conference on Phosphorus Chemistry, Cincinnati, Ohio, 12-17 July, 1998.

 

Innovation

Patents Filed

1. Liu, X.-W.; Chan-Park, M. B.; He, J.-X.; Le Mai Hoang, K.; Duan, H.; Yang, L. Biohybrid peptidoglycan oligomers. Publication no.: CN 112805305 A14 May 2021.

2. Liu, X.-W.; Chan-Park, M. B.; He, J.-X.; Le Mai Hoang, K.; Duan, H.; Yang, L. Biohybrid peptidoglycan oligomers. US Application No.: 17/267,2719 Feb.  2021.

3.       LIU Xue-Wei; CHAN Bee Eng Mary; HE Jingxi; LE MAI HOANG Kim; DUAN Hongwei; YANG Liang, Biohybrid Peptidoglycan Oligomers, PCT Application No. PCT/SG2019/050473, 2021. 26 March 2020 under publication no.: WO 2020/060491 A1

4. Yoon, H. S.; Rajan, S.; Toh, H. T.; Liu, X.-W.; Yao, H. Co-crystals of Nurr1-LBD In complex with a cyclopentenone prostaglandin and modulators of Nurr1. PCT Application No. PCT/SG2017/050476, 2020.

Patents Granted [Total: 10, Last 3 years: 3]

5. Liu, J.; Liu, X.-W.; Wei, X. Method of synthesizing anatase tio2 nanosheets. US 9663382 B2, May 30, 2017.

6. Liu, J.; Liu, X.-W.; Wei, X. Method of preparing a TiO2 nanostructure. US 9637394 B2, May 2, 2017.

7. Liu, X.-W.; Liu, J. An anode material for ultrafast-charging lithium ion batteries and a method of its synthesis. US 9,112,226 B2. Jan. 6, 2016

8. Yoon, H. S.; Liu, X.-W.; Harikishore, A. V. K. Tubulin inhibitors. WO2013162469 A1, October 31, 2013

9. Liu, X.-W.; Ma, J. Method of forming oseltamivir and derivatives thereof. US 8304553 B2. Nov 6, 2012.

10. Chen, J.; Nguyen, B. N.; Liu, X.-W.; Lopaschuk, G. D.; Dyck, J. R. Heterocyclic compounds as malonyl-CoA decarboxylase inhibitors. US 7696365 B2. Apr. 13, 2010.

11. Ebetino, F. H.; Liu, X.-W.; Solinsky, M. G.; Wos, J. A. Melanocortin receptor ligands. US 7026335 B2. Apr. 11, 2006.

12. Ebetino, F. H.; Liu, X.-W.; Solinsky, M. G.; Wos, J. A.; Mumin, R. N. N-Acyl piperidine derivatives for use as melanocortin receptor ligands in the treatment of feeding disorders. WO2003092690 A1. Nov. 13 2003.

13. McKenna, C. E.; Li, Z.; Liu, X.-W. Derivatives and analogs, US 6441214 B1. Aug. 27, 2002.

14. McKenna, C. E.; Li, Z.; Liu, X.-W. Synthesis and antiviral activity of a series of pyrophosphate analogs. US 6444837 B1. Licensed to Per Ardue Inc, Sept. 3, 2002.

Patents Licensed

15. McKenna, C. E.; Li, Z.; Liu, X.-W. Synthesis and antiviral activity of a series of pyrophosphate analogs. US 6444837 B1. Licensed to Per Ardue Inc, Sept. 3, 2002.