Publications on Platform Development
2015:
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- H J Diao, W C Low, R Q Lu, S Y Chew, 'Topographical effects on fiber-mediated microRNA delivery to control oligodendroglial precursor cells development', Biomaterials, 70, pp. 105-114, doi: 10.1016/j.biomaterials.2015.08.029
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- W C Low, P-O Rujitanaroj, D K Lee, J Kuang, P B Messersmith, J K Y Chan, S Y Chew, 'Mussel-inpsired modification of nanofibers for REST siRNA delivery: Understanding the effects of gene-silencing and substrate topography on human mesenchymal stem cell neuronal commitment', Macromolecular Bioscience, doi: 10.1002/mabi.201500101
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- L H Nguyen, H J Diao and S Y Chew, 'microRNAs and their potential therapeutic applications in neural tissue engineering', Advanced Drug Delivery Reviews, doi: 10.1016/j.addr.2015.05.007
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- H J Diao, W C Low, U Milberta, Q R Lu and S Y Chew, 'Nanofiber-mediated microRNA delivery to enhance differentiation and maturation of oligodendroglial precursor cells', Journal of Controlled Release, doi: 10.1016/j.jconrel.2015.03.005
2014:
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- X Jiang, M H Nai, C T Lim, C Le Visage, J K Y Chan, S Y Chew, 'Polysaccharide nanofibers with variable compliance for directingcell fate', Journal of Biomedical Materials Part A, Accepted. doi: 10.1002/jbm.a.35237
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- P Rujitanaroj, R Aid, S Y Chew* and C Le Visage, 'Polysaccharide electrospun fibers with sulfated poly(fucose) promote endothelial cell migration and VEGF-mediated angiogenesis', Biomaterials Science, 2, pp. 843, 2014. (*Co-corresponding author). doi: 10.1039/C3BM60245A.
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- X Jiang, R Mi, A Hoke, S Y Chew, 'Nanofibrous nerve conduit-enhanced peripheral nerve regeneration', J Tissue Eng Regen Med., 8(5), pp. 377-85, 2014. doi: 10.1002/term.1531.
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- S Rayatpisheh, D E Heath, A Shakouri, PO Rujitanaroj, S Y Chew, M B Chan-Park, 'Combining cell sheet technology and electrospun scaffolding for engineered tubular, aligned, and contractile blood vessels', Biomaterials, 35(9), pp. 2713-9, 2014. doi: 10.1016/j.biomaterials.2013.12.035.
2013:
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- W C Low, P Rujitanaroj, D K Lee, P B Messersmith, L W Stanton, E Goh and S Y Chew, 'Nanofibrous scaffold-mediated REST knockdown to enhance neuronal differentiation of stem cells', Biomaterials, 34 (14), pp. 3581-3590. doi:10.1016/j.biomaterials.2013.01.093.
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- W C Low, P Rujitanaroj, F Wang, J Wang and S Y Chew, 'Nanofiber-mediated release of retinoic acid and brain-derived neurotrophic factor for enhanced neuronal differentiation of neural progenitor cells', Drug Delivery and Translational Research, In press. doi: 10.10_07/s13346-013-0131-5.
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- P Rujitanaroj, B Jao, J Yang, J Wang, J M Anderson and S Y Chew, ‘Controlling fibrous capsule formation through long-term down-regulation of collagen type I (COL1A1) expression by nanofiber-mediated gene silencing’, Acta Biomaterialia, 9 (1), p. 4513-4524. doi: 10.1016/j.actbio.2012.09029.
2012:
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- Y Liu, S Rayatpisheh, S Y Chew, M B Chan-Park, 'Impact of endothelial cells on 3D cultured smooth muscle cells in a biomimetic hydrogel', ACS Appl Mater Interfaces. 2012 Mar;4(3):1378-87. doi: 10.1021/am201648f.
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- L Shi, R Aid, C Le Visage, S Y Chew, 'Biomimicking polysaccharide nanofibers promote vascular phenotypes: a potential application for vascular tissue engineering', Macromol Biosci., 12(3), pp. 395-401. doi: 10.1002/mabi.201100336.
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- T Liu, J D Houle, J Xu, B P Chan, S Y Chew, 'Nanofibrous collagen nerve conduits for spinal cord repair', Tissue Eng Part A., 18(9-10), pp. 1057-66. doi: 10.1089/ten.TEA.2011.0430.
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- X Jiang, H Q Cao, L Y Shi, S Y Ng, L W Stanton, S Y Chew, 'Nanofiber topography and sustained biochemical signaling enhance human mesenchymal stem cell neural commitment', Acta Biomater., 8(3), pp. 1290-302. doi: 10.1016/j.actbio.2011.11.019.
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- T Liu, J Xu, B P Chan, S Y Chew, 'Sustained release of neurotrophin-3 and chondroitinase ABC from electrospun collagen nanofiber scaffold for spinal cord injury repair', J Biomed Mater Res A. 100 (1), pp. 236-42. doi: 10.1002/jbm.a.33271.
2011:
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- P O Rujitanaroj, Y C Wang, J Wang J, S Y Chew, 'Nanofiber-mediated controlled release of siRNA complexes for long term gene-silencing applications', Biomaterials, 32(25), pp. 5915-23, 2011. doi: 10.1016/j.biomaterials.2011.04.065.
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- Handarmin, G J Y Tan, S Bibekananda, G T Marcy, E L K Goh and S Y Chew, 'Nanofibrous scaffold with incorporated protein gradient for directing neurite outgrowth', Drug Delivery and Translational Research, 1(2), pp. 147-160, 2011, doi:10.1007/s13346-011-0017-3.
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- L Shi, C Le Visage, S Y Chew, 'Long-term stabilization of polysaccharide electrospun fibres by in situ cross-linking', J Biomater Sci Polym Ed.. 22(11), pp.1459-72, 2011. doi: 10.1163/092050610X512108.
2010:
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- T Liu, W K Teng, B P Chan and S Y Chew, 'Photochemical Crosslinked Electrospun Collagen Nanofibers: Synthesis, Characterization & Neural Stem Cell Interactions', Journal of Biomedical Materials Research: Part A, 95(1), pp. 276-282, 2010. doi: 10.1002/jbm.a.32831.
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- H Q Cao, X Jiang, C Chai, S Y Chew, 'RNA interference by nanofiber-based siRNA delivery system', J Control Release, 144(2), pp. 203-12, 2010. doi: 10.1016/j.jconrel.2010.02.003.
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- X Jiang, S H Lim, H Q Mao, S Y Chew, 'Current applications and future perspectives of artificial nerve conduits',Current applications and future perspectives of artificial nerve conduits', Exp Neurol. 223(1), pp. 86-101, 2010. doi: 10.1016/j.expneurol.2009.09.009.
2009 & before:
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- H Q Cao, L Ting and S Y Chew, 'The Application of Nanofibrous Scaffolds in Neural Tissue Engineering', Advanced Drug Delivery Reviews, 61 (12), pp. 1055-64, 2009. doi: 10.1016/j.addr.2009.07.009.
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- S Y Chew, T G Park, 'Nanofibers in regenerative medicine and drug delivery', Adv Drug Deliv Rev., 61(12), pp. 987, 2009. doi: 10.1016/j.addr.2009.07.004. (Preface by Theme Editors).
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- I C Liao, S Y Chew and K W Leong , “Aligned core-shell nanofibers delivering bioactive proteins’, Nanomedicine, 1(4), pp. 465-471, 2006. doi: 10.2217/17435889.1.4.465. Download.
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- S Y Chew , R Mi, A Hoke and K W Leong, ‘Aligned protein-polymer composite fibers enhance nerve regeneration – A potential tissue engineering platform’, Advanced Functional Materials, 17, pp. 1288-1296, 2007. doi: 10.1002/adfm.200600441. Download.
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- S Y Chew , T C Hufnagel, C T Lim and K W Leong, ‘Mechanical properties of single electrospun drug-encapsulated nanofibers’, Nanotechnology, 17 (15), pp. 3880-3891, 2006. doi: 10.1088/0957-4484/17/15/045.
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- S Y Chew , Y Wen, Y Dzenis and K W Leong , ‘The role of electrospinning in the emerging field of nanomedicine’, Current Pharmaceutical Design, 12, pp. 4751-4770, 2006. doi: 10.2174/138161206779026326. Download.
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- S Y Chew , J Wen, E K F Yim and K W Leong, ‘Sustained release of proteins from electrospun biodegradable fibers’, Biomacromolecules, 6(4): 2017-2024, 2005. doi: 10.1021/bm0501149.