Publications on Understanding & Directing Cell Fate
2015:
- H J Diao, W C Low, R Q Lu, S Y Chew, 'Topographical effects on fiber-mediated microRNA delivery to control oligodendroglial precursor cells development', Biomaterials, 70, pp. 105-114, doi: 10.1016/j.biomaterials.2015.08.029
- W C Low, P-O Rujitanaroj, D K Lee, J Kuang, P B Messersmith, J K Y Chan, S Y Chew, 'Mussel-inpsired modification of nanofibers for REST siRNA delivery: Understanding the effects of gene-silencing and substrate topography on human mesenchymal stem cell neuronal commitment', Macromolecular Bioscience, doi: 10.1002/mabi.201500101
- H J Diao, W C Low, U Milberta, Q R Lu and S Y Chew, 'Nanofiber-mediated microRNA delivery to enhance differentiation and maturation of oligodendroglial precursor cells', Journal of Controlled Release, doi: 10.1016/j.jconrel.2015.03.005
2014:
- W W Yau, H Long, N C Gauthier, J K Chan and S Y Chew, 'The effects of nanofiber diameter and orientation on siRNA uptake and gene silencing', Biomaterials, 37C, pp. 94-106. doi: 10.1016/j.biomaterials.2014.10.003
- X Jiang, M H Nai, C T Lim, C Le Visage, J K Y Chan, S Y Chew, 'Polysaccharide nanofibers with variable compliance for directingcell fate', Journal of Biomedical Materials Part A, Accepted. doi: 10.1002/jbm.a.35237
- X Jiang, R Mi, A Hoke, S Y Chew, 'Nanofibrous nerve conduit-enhanced peripheral nerve regeneration', J Tissue Eng Regen Med., 8(5), pp. 377-85, 2014. doi: 10.1002/term.1531.
2013:
- W C Low, P Rujitanaroj, D K Lee, P B Messersmith, L W Stanton, E Goh and S Y Chew, 'Nanofibrous scaffold-mediated REST knockdown to enhance neuronal differentiation of stem cells', Biomaterials, 34 (14), pp. 3581-3590. doi:10.1016/j.biomaterials.2013.01.093.
- W C Low, P Rujitanaroj, F Wang, J Wang and S Y Chew, 'Nanofiber-mediated release of retinoic acid and brain-derived neurotrophic factor for enhanced neuronal differentiation of neural progenitor cells', Drug Delivery and Translational Research, In press. doi: 10.10_07/s13346-013-0131-5.
2012:
- H Cao, G Marcy, E L Goh, F Wang, J Wang, S Y Chew, 'The effects of nanofiber topography on astrocyte behavior and gene silencing efficiency', Macromol Biosci.,12(5), pp. 666-74, 2014. doi: 10.1002/mabi.201100436.
- W W Yau WW, PO Rujitanaroj, L Lam, S Y Chew, 'Directing stem cell fate by controlled RNA interference', Biomaterials, 33(9), pp. 2608-28. doi: 10.1016/j.biomaterials.2011.12.021.
- W C Low, W W Yau, L W Stanton, G Marcy, E L Goh, S Y Chew, 'Directing neuronal differentiation of primary neural progenitor cells by gene knockdown approach', DNA Cell Biol., 31(7), pp. 1148-60, 2012. doi: 10.1089/dna.2011.1557.
- L Shi, R Aid, C Le Visage, S Y Chew, 'Biomimicking polysaccharide nanofibers promote vascular phenotypes: a potential application for vascular tissue engineering', Macromol Biosci., 12(3), pp. 395-401. doi: 10.1002/mabi.201100336.
- T Liu, J D Houle, J Xu, B P Chan, S Y Chew, 'Nanofibrous collagen nerve conduits for spinal cord repair', Tissue Eng Part A., 18(9-10), pp. 1057-66. doi: 10.1089/ten.TEA.2011.0430.
- X Jiang, H Q Cao, L Y Shi, S Y Ng, L W Stanton, S Y Chew, 'Nanofiber topography and sustained biochemical signaling enhance human mesenchymal stem cell neural commitment', Acta Biomater., 8(3), pp. 1290-302. doi: 10.1016/j.actbio.2011.11.019.
2011:
- S Y Chew and W C Low, 'Scaffold-based approach to direct stem cell neural and cardiovascular differentiation: an analysis of physical and biochemical effects', J Biomed Mater Res A.;97(3), pp. 355-74, 2011. doi: 10.1002/jbm.a.33064.
- L Shi, C Le Visage, S Y Chew, 'Long-term stabilization of polysaccharide electrospun fibres by in situ cross-linking', J Biomater Sci Polym Ed.. 22(11), pp.1459-72, 2011. doi: 10.1163/092050610X512108.
2010:
- H Q Cao, X Jiang, C Chai, S Y Chew, 'RNA interference by nanofiber-based siRNA delivery system', J Control Release, 144(2), pp. 203-12, 2010. doi: 10.1016/j.jconrel.2010.02.003.
- H Q Cao, K McHugh, S Y Chew, J M Anderson, 'The topographical effect of electrospun nanofibrous scaffolds on the in vivo and in vitro foreign body reaction', J Biomed Mater Res A., 93(3), pp. 1151-9, 2010. doi: 10.1002/jbm.a.32609.
2009 & before:
- S Y Chew , R Mi, A Hoke and K W Leong, ‘The Effect of the Alignment of Electrospun Fibrous Scaffolds on Schwann Cell Maturation’, Biomaterials, 29 (6), pp. 653-661, 2008. doi: 10.1016/j.biomaterials.2007.10.025. Download.
- S Y Chew , R Mi, A Hoke and K W Leong, ‘Aligned protein-polymer composite fibers enhance nerve regeneration – A potential tissue engineering platform’, Advanced Functional Materials, 17, pp. 1288-1296, 2007. doi: 10.1002/adfm.200600441. Download.
