The development of Mirco Electro Mechanical Systems (MEMS) has enabled mirco miniaturization of machines which traditionally occupy a large volume space into chip scale level. There will be increasing demands for sophisticated control systems to be embedded into these micro machines to achieve truely integrated ``laboratory on a chip'' or even ``factory on a chip'' devices. A case in point is the concept of a biochip for biological and chemical analysis. One specific example of a biochip is the uPCR (micro-Polymerase Chain Reaction) bioreactor. This project aims to develop embedded control technology for miniaturized devices, We aim to develop tools and modules to
One motivation for using FPGA as a prototyping platform for embedded control of miniaturized devices is that the resulting design would contain the blueprint for the fabrication of the control systems. This provides a direct path towards the fabrication of tightly integrated miniaturized devices and their control systems. The uPCR bioreactor will be our targeted application which will serve to validate the proposed solutions and as a high-profile demonstrator of the technology. Model Predictive Control, or MPC as it is sometimes known, is our candidate control technology to be encapsulated in suitable FPGA modules. |
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About MPC MPC is a generic control technology which is more powerful
than the basic ``Proportional + Integral + Derivative'' (or PID) control
which is routinely used for process control. It is a suitable technology for
control problems which are too complex for a PID controller to solve
satisfactorily. For example, problems in which several variables which
interact with each other are to be controlled, problems in which the
performance specification is unusually high, problems in which significant
``dead-times'' occur, and --- above all --- problems in which there are
significant constraints that cannot or should not be violated by the
manipulated or the controlled variables. MPC remains relatively easy
to tune, compared with most other ``advanced control'' proposals, and this is
a major reason for proposing it as a generic technology, to complement
existing PID technology. Another reason is that recent developments indicate
that the formalism of MPC can be applied to so-called hybrid systems,
namely systems containing switchings, continuous and discrete states, with
design specifications often expressed in terms of dynamics response, logical
statements and constraints. This opens up an extremely wide and important range
of applications in all industrial and commercial sectors (manufacturing,
chemical and process, automotive, marine, aerospace, etc). MPC relies on solving
constrained optimization problems on-line. The computational load for such
problems is much greater than for traditional control algorithms. Some open
issues such as the packaging of the algorithm for an effective and flexible
device-application interface need to be studied. Algorithmic enhancement of
the control design techniques to allow a proper tradeoff between
computational load and the complexity of implementation will be investigated. |
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About PCR PCR was developed in 1985 by Kary B. Mullis, who was
awarded the 1993 Nobel Prize in chemistry for his work. It is used in DNA
fingerprinting and in medical tests to identify diseases from the infectious
agent's DNA. In forensic use, the test can be used to compare two samples of
DNA. PCR is also used in classification to help show evolutionary
relationships between organisms on the molecular level. The uPCR chip
promises improved temperature uniformity and reduced cycling time, together
with decreased sample and reagent volume consumption. Hence it has the
advantages of being able to be used even when only very small samples are
available, of faster operation, and of improved accuracy. This would provide
healthcare workers with portable and powerful devices which they can carry to
the field for timely detection of diseases with quick response to life
threatening situations. The use of semiconductor chip fabrication
technologies to fabricate such chips in large quantities would also result in
radical cost reduction. The realization of an embedded control for the uPCR bioreactor serves to demonstrate the applicability of the ``MPC on a chip'' concept. The current approaches to control system design for uPCR reactor rely on empirical and heuristic techniques, based on a combination of ingenuity and experience. We propose to develop a more analytical model-based approach using techniques from control theory, system identification and signal processing. These are theories that have been successfully applied in the aerospace and process control application. However, they have not been used in uPCR reactor. |
Project Title |
Principal
Investigator |
Funding |
Model
Predictive Control (MPC) on a Chip See
also A*STAR
EHS Booklet |
LING Keck Voon |
ASTAR (Ref: 022 106 0044) |
Automatic Code Embedment for Manufacturing Prognostics |
LING Keck Voon |
NTU-SIMTech project (Ref: U04-E-110B (Apr 2004 Apr 2006) |
Project Title |
Principal
Investigator |
Funding |
LING
Keck Voon CH'NG
WEI LUEN LEE
CHUNG HONG, ANDY |
FYP4039 |
Project Title |
Principal
Investigator |
Funding |
MPC on a chip |
LING Keck Voon |
ASTAR (Ref: 012 106 0055) |
Investigation
of FPGA Technology for Embedded System Applications |
LING
Keck
Voon |
FYP |