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Abstract:
Pediatric
acute lymphoblastic leukemia (ALL) is one of the great success stories
of modern
cancer therapy, with risk-stratified treatment protocols achieving
nearly 80% cure rates.
However, the risk stratification is an imprecise and labour intensive,
requiring the combined
expertise of multiple specialists. In this talk, we discuss the
development of a single-test
platform based on gene expression microarray and computational analysis
to address this
problem.
This
talk is based on joint work with Jinyan Li, Huiqing Liu, and Allen
Yeoh.
Speaker:
Limsoon
Wong is Deputy Executive Director (Research) of the Institute for
Infocomm Research.
Before assuming his current position, he led one of Asia’s
most productive and most advanced
bioinformatics research laboratory for nearly a decade. Besides
bioinformatics, Limsoon is also
well known for his fundamental contributions to query language theory
and finite model theory.
He has published close to 100 papers in these 3 fields, and several
of his papers are among the
best cited in each of these three fields. He is a managing editor
of "Journal of Bioinformatics and
Computational Biology" and is an advisory editor of "BIOSILICO".
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