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Abstract:
Neurocomputing
(NC) is an area of computer science and engineering concerned with
the
development, implementation, realisation and application of computational
models that mimic
the functioning of the brain in its main functions of adaptive learning,
predictive generalisation,
and knowledge discovery. Applications span across all disciplines.
This talk presents applications
in Bioinformatics. The first part of the talk presents challenging
problems in Bioinformatics. The
second part presents solutions with the use of neurocomputing and
hybrid methods that include
also statistical methods, support vector machines, fuzzy logic and
evolutionary computation. As <
special methods for adaptive learning and data and knowledge integration,
evolving connectionist
systems (ECOS) are presented and applied [1]. Solutions are demonstrated
with the use of a
neurocomputing environment NeuCom (www.theneucom.com) developed
by the Knowledge Engineering
and Discovery Research Institute (KEDRI) (www.kedri.info). Applications
in bioinformatics and medical
decision support are presented, that includes: gene expression data
analysis for cancer and other
disease profiling; promoter recognition modelling gene regulatory
networks; integrating gene and
clinical data; cardio-vascular risk prognosis; renal function evaluation;
ontology builder for bioinformatics;
and
others.
References
[1] N.Kasabov, Evolving Connectionist Systems: Methods and Applications
in Bioinformatics, Brain Study
and Intelligent Machines, Springer Verlag, 2002 (www.springer.de)
[2] Kasabov, N. and D. Dimitrov. A
method for gene regulatory network modelling with the use of evolving
connectionist systems. Proc.
of ICONIP'2002 - International Conference on Neuro-Information Processing,
Singapore, November 2002,
IEEE Press (2002)
Speaker
Nikola Kasabov, FRSNZ, FNZCS, Senior MIEE, PhD - Sofia, is Professor
of Knowledge Engineering in the
School of Computer and Information Sciences at the Auckland University
of Technology, New Zealand,
and the Founding Director of the Knowledge Engineering and Discovery
Research Institute (KEDRI)
(www.kedri.info). Previously he held Professor positions at the
University of Otago and the Technical
University in Sofia, Bulgaria. He has published more than 15 monograph
and textbooks, 350 papers in
refereed journals and conference proceedings, 28 patents. He is
recipient of the Silver Medal for Science
and Technology of the RSNZ, New Zealand. He is a board member of
the Asia Pacific Neural Network
Assembly (APNNA) and was its President in 1997/98. Kasabov is on
the editorial boards of 7 international
journals
and has been on the PC of 50 international conferences in the last
5 years. He chaired the series
of ANNES conferences (1993 - 2001).
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