Abstract:
Protein-protein interactions represent one of the most
diverse set of phenomenon found in nature. An analysis of protein-protein
interactions is critical for understanding of pathways. There are a variety
of methods that are used to generate interactions data. It is the integration
of this data, which will help to highlight the correct information. There
are many existing methods that have already been implemented as well as
others that are in the process of implementation.
The current and future work, which will create the framework for a better
understanding of these protein-protein interactions, will be discussed.
Speaker
Prasanna Kolatkar (PK) is currently at the Genome Institute of Singapore
as Group Leader.
PK previously held appointments at the Bioinformatics Centre-IMCB and
Bioinformatics Centre.
PK obtained his undergraduate degree at Augustana College, Rock Island,
IL in 1985 and PhD at The University of Texas at Austin in 1991 in Dept
of Chemistry. Subsequently he was a post-doc with Michael Rossmann at
Purdue University till 1997.
PK also obtained the following awards: EAKIN Award for Research Excellence
(Graduate Research), 1991; Jane Coffin Childs Memorial Fund for Medical
Research (Post-doc) 1992-1995;
Outstanding University Research Award, NUS in 1999. Recently he has been
involved with production of a pipeline for annotating zebrafish transcriptome
and has implemented and additionally developing a database to help store
and analyze protein-protein interactions. He is also undertaking projects
dealing with X-ray crystallography and merging this information with the
protein-protein interactions database.
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