Heterotroph: Catabolism & ATP Production

  

(energy transforms from long-term chemical energy to short-term chemical energy and heat energy)

As to heterotroph, energy production accompanies with catabolism of organic macromolecules in their cell. The main three macromolecules, which can provide energy for surviving heterotroph cells, are carbohydrates, proteins and fats. The following schematic shows their catabolism pathways and ATP production in a cell. During the process, part of the long-term energy is transformed into short-term chemical energy (ATP), and the other is lost as heat energy. The carbohydrates are the first substrate that is burned to provide energy for the cell. Moreover, the catabolism of carbohydrates is the most important parts. Carbohydrates, proteins and fats catabolisms are combined together via Krebs cycle. Here we focus on the catabolism of carbohydrates and the energy production in this process.

 

                   

 

Glycolysis: (Cartoon here!!)

Conduct in cytosol

Glucose         2pyruvate

Net result = 2ATP and 2NADH

ATP is produced substrate level phosphorylation

 

                                                 http://www.sc.chula.ac.th/courseware/2303101j/XII-energy-transformation.pdf

 

Krebs cycle:

     Conduct in matrix of mitochondria

     1 acetyl CoA yields

3NADH + H+

1 FADH2

1ATP

2CO2

(Large quantity of electron carriers are produced)

 

ghs.gresham.k12.or.us/.../resp/notes/krebs2.htm

 

Electron transport chain and oxidative phosphorylation: (Cartoon here!!)

     inner membrane of mitochondria

     electron is transferred to electron acceptor with higher affinity (more

electronegative)

     O2, the most electronegative electron acceptor, is the final electron

acceptor

     free energy was released during electron transfer

     H+ was pumped across the membrane by the free energy released by the electron transfer (from matrix to the intermembrane space)

     H+ flow back to the matrix by a channel in ATP synthase

     free energy released from the H+ flow is used to synthesize ATP