Associate Professor Dong-An WANG

Zhang, F., Yao, Y. C., Hao, J. H., Zhou, R. J., Liu, C. Z., Gong, Y. H., Wang, D. A.*, “A dual-functioning adenoviral vector encoding both transforming growth factor-β3 and shRNA silencing type I collagen: construction and controlled release for chondrogenesis”, Journal of controlled Release, in press. DOI: 10.1016/j.jconrel.2009.09.027
Wang, C. M., Adrianus, G. N., Sheng, N., Toh, S. K., Gong, Y. H., Wang, D. A.* “In vitro performance of an injectable hydrogel / microsphere based immunocyte delivery system for localised anti-tumour activity”, Biomaterials, in press. DOI: 10.1016/j.biomaterials.2009.09.006
Shi, X. T., Wang, Y. J., Varshney, R. R., Ren, L., Zhang, F., Wang, D. A.*, “In Vitro Osteogenesis of Synovium Stem Cells Induced by Controlled Release of Bisphosphate Additives from Microspherical Mesoporous Silica Composite”, Biomaterials, 30 (2009), 23-24: 3996-4005.
Hao, J. H., Varshney, R. R., Wang, D. A.*, “Engineering Osteo/Chondrogenesis with Gene-Enhanced Therapeutic Cells”, Current Opinion in Molecular Therapeutics, 11 (2009), 4: 404-410.
Gong, Y. H., Wang, C. M., Lai, R. C., Su, K., Zhang, F., Wang, D. A.*, “A novel injectable polysaccharide hydrogel: modified gellan gum for long-term cartilage regeneration in vitro”, Journal of Materials Chemistry, 19 (2009), 14: 1968-1977.
Fan, J. B., Varshney, R. R., Ren, L., Cai, D. Z., Wang, D. A.*, “Synovium-Derived Mesenchymal Stem Cells: A New Cell Source for Musculoskeletal Regeneration”, Tissue Engineering Part B Reviews, 15 (2009), 1: 75-86.
Wang, C. M., Gong, Y. H., Zhong, Y., Yao, Y.C., Su, K., Wang, D. A.*, “The control of anchorage-dependent cell behavior within a hydrogel / microcarrier system in an osteogenic model”, Biomaterials, 30 (2009), 13: 2259-2269.
Yao, Y. C., Wang, C. M., Varshney, R. R., Wang, D. A.*, “Antisense makes sense in engineered regenerative medicine”, Pharmaceutical Research, 26 (2009), 2: 263-275.
Shi, X. T., Wang, Y., J., Ren, L., Gong, Y. H., Wang, D. A.*, “Enhancing alendronate release from a novel PLGA/hydroxyapatite microspheric system for bone repairing applications”, Pharmaceutical Research, 26 (2009), 2: 442-430.
Hao, J. H., Varshney, R. R., Wang, D. A.*, “TGF-β3: A Promising Growth Factor in Engineered Organogenesis”, Expert Opinion on Biological Therapy, 8 (2008), 10:1485-1493.
Hao, J. H., Yao, Y. C., Varshney, R. R., Wang, L. C., Prakash, C., Li, H., Wang, D. A.*, “Gene Transfer and Living Release of Transforming Growth Factor-Beta 3 for Cartilage Tissue Engineering Applications”, Tissue Engineering Part C Methods, 14 (2008), 4: 273-280
Liu, Y., Ramanath, H. S., Wang, D. A.*, “Tendon Tissue Engineering Using Scaffold Enhancing Strategies”, Trends in Biotechnology, 26 (2008), 4: 201-209.
Wang, D. A.*, “Engineering Blood-Contact Biomaterials by ‘H-Bond Grafting’ Surface Modification”, In: “Functional Materials & Biomaterials”, Advances in Polymer Science, Vol.209 (2007), p179-227.
Wang, D. A., Varghese, S., Sharma, B., Strehin, I., Fermanian, S., Gorham J., Fairbrother, H.D, Cascio B, Elisseeff, J.H.*, “Multifunctional Chondroitin Sulphate for Cartilage Tissue-Biomaterial Integration”, Nature Materials, 6 (2007), 5: 385-392

	Associate Professor Dong-An WANG
	Division of Bioengineering Nanyang Technological University Singapore 637457 Tel: (65) 6316 8890 Fax: (65) 6791 1761 Email: DAWang@ntu.edu.sg
	Education:
	B.Eng., Zhejiang University Ph.D., Zhejiang University

	Research focus:
	Functional biomaterials/bio-composite for therapeutic cell delivery; Nucleic acid (gene and antisense) delivery for therapeutic engineering; Adjacent reproducible tissue sourced stem/progenitor cells for engineered tissue regeneration; Tissue-biomaterial integration;

	Selected publications:
	Zhang, F., Yao, Y. C., Hao, J. H., Zhou, R. J., Liu, C. Z., Gong, Y. H., Wang, D. A., “A dual-functioning adenoviral vector encoding both transforming growth factor-β3 and shRNA silencing type I collagen: construction and controlled release for chondrogenesis”, Journal of controlled Release, in press. DOI: 10.1016/j.jconrel.2009.09.027 Wang, C. M., Adrianus, G. N., Sheng, N., Toh, S. K., Gong, Y. H., Wang, D. A. “In vitro performance of an injectable hydrogel / microsphere based immunocyte delivery system for localised anti-tumour activity”, *Biomaterials, in press. DOI: 10.1016/j.biomaterials.2009.09.006 Shi, X. T., Wang, Y. J., Varshney, R. R., Ren, L., Zhang, F., Wang, D. A., “In Vitro Osteogenesis of Synovium Stem Cells Induced by Controlled Release of Bisphosphate Additives from Microspherical Mesoporous Silica Composite”, *Biomaterials, 30 (2009), 23-24: 3996-4005. Hao, J. H., Varshney, R. R., Wang, D. A., “Engineering Osteo/Chondrogenesis with Gene-Enhanced Therapeutic Cells”, Current Opinion in Molecular Therapeutics*, 11 (2009), 4: 404-410. Gong, Y. H., Wang, C. M., Lai, R. C., Su, K., Zhang, F., Wang, D. A., “A novel injectable polysaccharide hydrogel: modified gellan gum for long-term cartilage regeneration in vitro”, *Journal of Materials Chemistry, 19 (2009), 14: 1968-1977. Fan, J. B., Varshney, R. R., Ren, L., Cai, D. Z., Wang, D. A., “Synovium-Derived Mesenchymal Stem Cells: A New Cell Source for Musculoskeletal Regeneration”, *Tissue Engineering* Part B Reviews, 15 (2009), 1: 75-86. Wang, C. M., Gong, Y. H., Zhong, Y., Yao, Y.C., Su, K., Wang, D. A., “The control of anchorage-dependent cell behavior within a hydrogel / microcarrier system in an osteogenic model”, Biomaterials, 30 (2009), 13: 2259-2269. Yao, Y. C., Wang, C. M., Varshney, R. R., Wang, D. A., “Antisense makes sense in engineered regenerative medicine”, *Pharmaceutical Research, 26 (2009), 2: 263-275. Shi, X. T., Wang, Y., J., Ren, L., Gong, Y. H., Wang, D. A., “Enhancing alendronate release from a novel PLGA/hydroxyapatite microspheric system for bone repairing applications”, *Pharmaceutical Research, 26 (2009), 2: 442-430. Hao, J. H., Varshney, R. R., Wang, D. A., “TGF-β3: A Promising Growth Factor in Engineered Organogenesis”, Expert Opinion on Biological Therapy*, 8 (2008), 10:1485-1493. Hao, J. H., Yao, Y. C., Varshney, R. R., Wang, L. C., Prakash, C., Li, H., Wang, D. A., “Gene Transfer and Living Release of Transforming Growth Factor-Beta 3 for Cartilage Tissue Engineering Applications”, *Tissue Engineering* Part C Methods, 14 (2008), 4: 273-280 Liu, Y., Ramanath, H. S., *Wang, D. A., “Tendon Tissue Engineering Using Scaffold Enhancing Strategies”, Trends in Biotechnology, 26 (2008), 4: 201-209. Wang, D. A.*, “Engineering Blood-Contact Biomaterials by ‘H-Bond Grafting’ Surface Modification”, In: “Functional Materials & Biomaterials”, Advances in Polymer Science, Vol.209 (2007), p179-227. Wang, D. A.*, Varghese, S., Sharma, B., Strehin, I., Fermanian, S., Gorham J., Fairbrother, H.D, Cascio B, Elisseeff, J.H., “Multifunctional Chondroitin Sulphate for Cartilage Tissue-Biomaterial Integration”, *Nature Materials*, 6 (2007), 5: 385-392

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