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Dr Liew Choong-Chin
刘宗正博士
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Nanyang Distinguished Alumni Award Recipient (2005)
南洋卓越校友奖获奖者 (2005)
Dr Liew Choong-Chin 刘宗正博士
Scientist Par Excellence
A pioneer in cardiovascular molecular medicine in the 1980s and 1990s, Dr Liew Choong-Chin remains a leader in disease-specific genomics research. Together with his colleagues at the University of Toronto and Brigham and Women's Hospital, Dr Liew was the first to estimate the number of genes in the cardiovascular system and developed the first cardiovascular-specific microarray (CardioChip) for studying the mechanisms of cardiovascular disease. Most recently, Dr Liew has developed the Sentinel Principle, the novel concept behind a system-wide technology with applications for diagnosing disease at the molecular level through the identification of disease-specific biomarkers from blood.
Currently Dr Liew is chief scientist of ChondroGene Ltd, which he co-founded. The firm is developing diagnostic tests for diseases based on the Sentinel Principle, for cancer, central nervous system disorders, cardiovascular diseases and arthritis. Dr Liew is also Professor Emeritus, Department of Laboratory Medicine and Pathobiology and founder of the Cardiac Gene Unit, University of Toronto, as well as Visiting Professor of Medicine and Founding Director of the Cardiovascular Genome Centre at Brigham and Women's Hospital, Harvard Medical School.
Born in Malaysia and educated in Singapore, Dr Liew graduated from Nanyang University in 1960 with a Bachelor of Science in Biology. After receiving his M.A. in Physiology and Ph.D. in Pathological Chemistry from University of Toronto in 1967, he joined the university's Faculty of Medicine. His early career focused on the investigation of the biochemistry of heart nuclei in relation to myocardial development and cardiac hypertrophy.
Together with his students, postdoctoral fellows and collaborating researchers, Dr Liew has published more than 300 original scientific papers, monographs and abstracts. Dr Liew has received some 20 honorary professorships, including professorships from Peking Union Medical College, the Chinese Academy of Medical Sciences, Peking University, and the Chinese University of Hong Kong. He received the Canadian Society of Clinical Chemists Research Excellence Award in 1998. In 2002, the International Academy of Cardiovascular Sciences honoured him as the first recipient of the Makoto Nagano Award for Achievements in Cardiovascular Education.
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